59-26-7 structure, C10H14N2O
N,N-Diethylnicotinamide
CAS No.: 59-26-7 Formula: C10H14N2O Molecular Weight: 178.23100
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N,N-Diethylnicotinamide

CAS No.:

59-26-7

Formula:

C10H14N2O

Molecular Weight: 178.23100
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Description

Nikethamide is a stimulant which mainly affects the respiratory cycle. Widely known by its former trade name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overdoses, before the advent of endotracheal intubation and positive-pressure lung expansion. It is now considered to be of no value for such purposes, and may be dangerous.
In alternate terminology, it is known as nicotinic acid diethylamide, which meaningfully emphasizes its laboratory origins, and of which its common name is derived as a blend.

Basic Info

Chemical Name

N,N-Diethylnicotinamide

Synonyms

3-Pyridinecarboxamide, N,N-diethyl-; N,N-diethylpyridine-3-carboxamide; Nikethamide;

CAS No.

59-26-7

Molecular Formula

C10H14N2O

Molecular Weight

178.23100

PSA

33.20000

LogP

1.56360

Numbering system

MDL number MFCD00006386

Properties

Appearance & Physical State

clear colorless to yellow liquid

Density

1.06

Boiling Point

296-300ºC

Melting Point

24-26ºC

Flash Point

141.1ºC

Refractive Index

n20/D 1.524(lit.)

Safety Info

RTECS

QS4375000

Hazard Class

6.1(b)

Safety Statements

S23-S24

HS Code

2933399090

Packing Group

III

WGK Germany

3

RIDADR

UN 2811 6.1/PG 3

Risk Statements

R23/24/25

Hazard Codes

T

Signal Word

Danger

Caution Statement

P261; P301 + P310; P305 + P351 + P338

Hazard Declaration

H301; H315; H319; H335

Symbol

GHS06
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