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552-94-3 structure, C14H10O5
salsalate
CAS No.: 552-94-3 Formula: C14H10O5 Molecular Weight: 258.22600
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552-94-3 structure, C14H10O5

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552-94-3 structure, C14H10O5

salsalate

CAS No.:

552-94-3

 Formula:

C14H10O5

 Molecular Weight: 258.22600
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Description

Salsalate is a medication that belongs to the salicylate and non-steroidal anti-inflammatory drug (NSAID) classes. Relative to other NSAIDs, salsalate has a weak inhibitory effect on the cyclooxygenase enzyme and decreases the production of several proinflammatory chemical signals such as interleukin-6, TNF-alpha, and C-reactive protein. The mechanism through which salsalate is thought to reduce the production of these inflammatory chemical signals is through the inhibition of IκB kinase resulting in decreased action of NF-κB genes. This mechanism is thought to be responsible for salsalate's insulin-sensitizing and blood sugar lowering properties. Salsalate is the generic name of a prescription drug marketed under the brandnames Mono-Gesic, Salflex, Disalcid, and Salsitab. Other generic and brand name formulations may be available.

Numbering system

UNII V9MO595C9I

Properties

Appearance & Physical State

 crystals

Density

 1.404g/cm3

Boiling Point

 482.9ºC at 760 mmHg

Melting Point

 148-151ºC

Flash Point

 188ºC

Stability

 Stable at room temperature in closed containers under normal storage and handling conditions.

Storage Condition

 Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Safety Info

Safety Statements

 S26-S37/39

HS Code

 2918230000

Risk Statements

 R36/37/38

Hazard Codes

 Xi
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Precursor:
Sodium salicylate O-Acetylsalicylryl chloride 1-methyl-4-nitrosobenzene salicylic acid ACETYLSALICYLSALICYLIC ACID 1,4-Dioxane (2-acetoxy-benzoyl)-carbonic acid ethyl ester disalicylide (2-acetyloxybenzoyl) 2-acetyloxybenzoate Aspirin
Product:
2-[2-[10-[2-(2-carboxyphenoxy)carbonylphenoxy]-10-oxodecanoyl]oxybenzoyl]oxybenzoic acid (2-carbonochloridoylphenyl) 2-hydroxybenzoate ethyl 2-[(2-hydroxybenzoyl)amino]acetate salicylic acid ACETYLSALICYLSALICYLIC ACID
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Compound Synonyms: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 1 2 3 4 5 6 7 8 9

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