gemifloxacin

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: gemifloxacin
CAS No.: 175463-14-6 Formula: C18H20FN5O4 Molecular Weight: 389.38100
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CAS No.:
175463-14-6
Formula:
C18H20FN5O4
Molecular Weight: 389.38100

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Overview
Description
Basic Info
Numbering system
Properties
Safety Info
Synthesis Route
Precursor

Description

Gemifloxacin mesylate (trade name Factive, Oscient Pharmaceuticals) is an oral broad-spectrum quinolone antibacterial agent used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. Vansen Pharma Inc. has licensed the active ingredient from LG Life Sciences of Korea.

Basic Info

Chemical Name	gemifloxacin
Synonyms	(R,S)-7-(3-aminomethyl-4-syn-methoxyimino-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid; Gemifloxactin; 7-[3-(Aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Mesilate; Gemifioxacin; Gemifloxacin Mesilate; 7-(3-Aminomethyl)-4-methoxyimino-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1; 7-[3-(aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid; Gemifloxacin; 7-[(4Z)-3-(aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphtyridine-3-carboxylic acid; 7-[(4Z)-3-(aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid; 7-(3-Aminomethyl)-4-methoxyimino-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid; Expand
CAS No.	175463-14-6
Molecular Formula	C18H20FN5O4
Molecular Weight	389.38100
PSA	123.04000
LogP	1.73130

Numbering system

MDL number	MFCD07779399

Properties

Appearance & Physical State	powder
Density	1.64g/cm3
Boiling Point	638.9ºC at 760mmHg
Flash Point	340.2ºC
Refractive Index	1.735
Vapor Pressure	0mmHg at 25°C

Safety Info

HS Code	2933990090

Synthesis Route

Total 8 Documents >>

: 44981-94-4
N-(2-Cyanoethyl) GlycineEthyl Ester

: 175463-14-6
gemifloxacin

Detail>>

Precursor

Total 8 Documents >>

: 266353-18-8
N-tert-butoxycarbonyl-2-(2-cyanoethyl)aminoacetic acid ethyl ester

: 773826-73-6
tert-butyl 3-(aminomethyl)-4-hydroxypyrrolidine-1-carboxylate

: 197143-33-2
tert-butyl 3-cyano-4-hydroxypyrrolidine-1-carboxylate

: 175463-32-8
1-Boc-3-cyano-4-oxopyrrolidine

More >>

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