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Compound | 2'-deoxyguanosine | ||||
---|---|---|---|---|---|
CAS No. | 961-07-9 | Catalog No. | XMZX-W20295 | Brand | |
Purity | 99% | Packing | 25kg/DRUMS | Grade | |
Lead Time | 3Day (s) | Origin | Loading Port |
Boiling Point | 725.5ºC at 760mmHg |
---|---|
Stability | Stable under normal temperatures and pressures. |
Storage Condition | Store at RT. |
Appearance & Physical State | white crystalline powder |
Refractive Index | -42 ° (C=0.2, 1mol/L NaOH) |
Density | 2.08g/cm3 |
Melting Point | 300ºC |
Uses Nucleoside analog
Uses Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.
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