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Home >  Chemical Encyclopedia > Miscellaneous > Chemical Reagents > Halides > 6-bromocyclohex-4-ene-1,2,3-triol
42014-74-4 structure, C6H9BrO3
6-bromocyclohex-4-ene-1,2,3-triol
CAS No.: 42014-74-4 Formula: C6H9BrO3 Molecular Weight: 209.03800
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42014-74-4 structure, C6H9BrO3

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42014-74-4 structure, C6H9BrO3

6-bromocyclohex-4-ene-1,2,3-triol

CAS No.:

42014-74-4

 Formula:

C6H9BrO3

 Molecular Weight: 209.03800
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Description

Bromoconduritol selectively inhibits mammalian alpha-glucosidase 2 (Glc2/Glc1 glucosidase in the glycoprotein processing pathway), yeast alpha-glucosidase, and some beta-glucosidases. It does not inhibit mammalian alpha-glucosidase 1 (Glc3-glucosidase) or mammalian Golgi mannosidase 1 (alpha-1,2-specific) in the glycoprotein processing pathway; the formation of lipid-linked oligosaccharide precursor (dolichol pyrphosphate oligosaccharide) and the transfer of lipid-linked oligosaccharide to proteins. Preparations in ice-cold H2O should be used immediately. The half-time for decomposition of bromoconduritol A (debromination) is 16 min (H2O, pH 7.3, 37oC). Under similar conditions, the half-life of bromoconduritol B is 2 mins. Working concentration for the inhibition of glycoprotein processing in vivo or in vitro is 2.5-5.0 mM. Bromoconduritol may be used to alter the oligosaccharide chain composition of glycoproteins for studies on the role of oligosaccharides (especially hybrid or complex type oligosaccharides) in the transportability and function of glycoproteins.

Basic Info

Chemical Name

 6-bromocyclohex-4-ene-1,2,3-triol

Synonyms

OR6825T; Bromconduvit; 6-bromoconduritol; Bromoconduritol;

CAS No.

 42014-74-4

Molecular Formula

 C6H9BrO3

Molecular Weight

 209.03800

PSA

 60.69000

LogP

 -0.59760

Properties

Density

 1.989g/cm3

Boiling Point

 291.6ºC at 760 mmHg

Melting Point

 115-118ºC

Flash Point

 130.1ºC

Refractive Index

 1.682

Storage Condition

 2-8ºC

Safety Info

HS Code

 2906199090
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Compound Synonyms: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 1 2 3 4 5 6 7 8 9

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