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Hebei Yingong New Material Technology Co., Ltd

Hebei Yingong New Material Technology Co., Ltd

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China Hebei Shijiazhuang
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0086 18032048384
18032048384

Catalog No. : 1

Alogliptin benzoate

  • 850649-62-6
  • 1kg
  • yingong
  • 99%
Packing :
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Price :
US $1.00 /1kg MOQ 1kg
  • Product Details & Description

Product Info

Compound alogliptin benzoate
CAS No. 850649-62-6 Catalog No. 1 Brand yingong
Purity 99% Packing 1kg Grade
Lead Time Origin Loading Port

PropertiesMore

Boiling Point 671.2ºC at 760 mmHg
Appearance & Physical State white powder
Flash Point 359.7ºC

Description

Common NameAlogliptin benzoate

CAS Number850649-62-6

Molecular Weight461.513

Boiling Point671.2ºC at 760 mmHg

Molecular FormulaC25H27N5O4



Use of Alogliptin benzoate

Alogliptin benzoate(SYR 322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.IC50 value: <10 nMTarget: DPP4Alogliptin is an orally administered, anti-diabetic drug in the DPP-4 inhibitor class. A randomized clinical trial reporting in 2011 aimed to determine the efficacy and safety of alogliptin versus placebo and voglibose among newly diagnosed Type 2 diabetes patients in Japan. The main outcome indicated that alogliptin was statistically superior to both comparitors. A randomized clinical trial reporting in 2012 aimed to demonstrate that alogliptin was "non-inferior" to a "very low fat/calorie traditional Japanese diet" among newly diagnosed Type 2 diabetes patients in Japan. The outcome indicated that both the drug and dietary treatments comparably impacted indicators of the diabetic condition, such as HbA1c levels and glycemic efficacy. The drug treatment had its impact without changing body mass index (BMI), but the dietary treatment was accompanied by a significant reduction in the BMI…

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Alogliptin benzoate

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850649-62-6

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