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| Compound | Pentoxifylline | ||||
|---|---|---|---|---|---|
| CAS No. | 6493-05-6 | Catalog No. | XMZX-W416 | Brand | |
| Purity | 99% | Packing | 25kg/DRUMS | Grade | |
| Lead Time | 3Day (s) | Origin | Loading Port | China,Xiamen,Siming District | |
| Boiling Point | 531.3ºC at 760mmHg |
|---|---|
| Storage Condition | Store at RT |
| Appearance & Physical State | White to off-white solid |
| Flash Point | 275.1ºC |
| Density | 1.31g/cm3 |
| Melting Point | 98-100ºC |
Chemical Properties White to Off-White Solid
Originator Trental,Albert Roussel ,W. Germany ,1972
Uses A metabolite of Pentifylline. Methylxanthine derivative that improves blood flow by decreasing blood viscosity. Phosphodiesterase inhibitor. Inhibits the synthesis of tumor necrosis factor a (TNF-a)
Uses Pentoxifylline can increase red blood cell deformability, reduce blood viscosity, and decrease platelet aggregation and thrombus formation. Pentoxifylline is an oral agent that improves perfusion of occluded vessels and is used to treat systemic vascular diseases. The retinal flow velocity in patients with RVO treated with pentoxifylline improved compared with placebo, but the study had a small number of patients (n = 8) and short follow-up (4 weeks), and no visual outcome data were reported.
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