Procurement Request
Home>Supplier>Simagchem Corp.>Epothilone B

Simagchem Corp.

Simagchem Corp.

Certified Store
Custom-Made
China Fujian Xiamen
cs4@simagchem.com
13806087780
-592-2680277

Catalog No. : XMZX-W5097

Epothilone B

  • 152044-54-7
  • 25kg/DRUMS
  • 99%
  • China,Xiamen,Siming District
  • 3Day (s)
Packing :
More

Request For Quotation

  • Product Details & Description

Product Info

Compound epothilone B
CAS No. 152044-54-7 Catalog No. XMZX-W5097 Brand
Purity 99% Packing 25kg/DRUMS Grade
Lead Time 3Day (s) Origin Loading Port China,Xiamen,Siming District

PropertiesMore

Boiling Point 680.2ºC at 760mmHg
Appearance & Physical State white Powder
Flash Point 365.2ºC
Refractive Index 1.532
Density 1.136
Melting Point 95-97ºC
Vapor Pressure 0mmHg at 25°C

Description

Chemical Properties White Powder

Uses Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. Epothilone B is what is known as a microtubule stabilizer. When a cell divides, the chromosomes that will end up in each cell are separated by thin filaments called microtubules. Normally these microtubules then break down as the cell division progresses. This class of cytotoxic chemo drugs prevents that break down and thus prevents cells from completing division.

Uses Epothilone B is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum. Like epothilone A, epothilone B acts by stabilising microtubule formation at the taxol binding site, and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity.

Uses Epothilone B (Epo B) is a macrolide that causes the formation of bundles of intracellular microtubules in non-mitotic cells, induces the formation of hyperstable tubulin polymers, and arrests cell cycling in mitosis. It induces mitotic arrest at the G2-M transition in Hs578T and HeLa cells (IC50 = 3 and 32 nM, respectively) as well as in multidrug resistant KB3-1 and KBV-1 cells (IC50 = 16 and 92 nM, respectively). Epo B causes cell cycle arrest at nanomolar IC50 values in cell lines from ovarian, breast, lung, colon, prostate, and squamous cancer.

Request For Quotation

Product

Epothilone B

Cas No

152044-54-7

*Purity
*Quantity
*Valid for
*Shipping To
Contact Person
*Email
*Company/Institute
Notes

I would like to have suppliers recommended by MOLBASE.

I agree to share my contact information to the supplier(s).

Other Supplier Reference

Product Name Purity Packing Lead Time Country Store Name Details
Epothilone 99.99% 25kg,200kg 3 spec 1Day (s) China,Hebei
HeBei GuanLang Biotechnology Co.,Ltd
Request For Quotation
epothilone B 99% 1kg IN STOCK China,Henan
HENAN LIHAO CHEM LIMITED
Request For Quotation
epothilone B 98% 1mg 7Day (s) China,Shanghai Shanghai Chengshao Biological Technology Co., Ltd. Request For Quotation
4,17-Dioxabicyclo[14.1.0]heptadecane-5,9-dione,7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-,(1S,3S,7S,10R,11S,12S,16R)- 99% 25kg,25kg 7Day (s) China,Henan
Henan Tianfu Chemical Co.,Ltd
Request For Quotation
Patupilone 0.98 5g 3Day (s) China,Henan
Henan Coreychem Co.,Ltd
Request For Quotation
epothilone B 99% 100g,50g 3 spec 7Day (s) China,Jiangsu
nanjing pars Chemical Co.,Ltd
Request For Quotation
Patupilone 98% 25kg 1Week (s) China,Chongqing
chemdad
Request For Quotation
epothilone B 98% 1mg,5mg 30Day (s) China,Shanghai Shanghai Jizhi Biochemical Technology Co., Ltd. Request For Quotation
epothilone B 99% 10g 7Day (s) China,Hubei hubei wei de li hua xue ke ji you xian gong si Request For Quotation
epothilone B 98% 1kg,1吨 7Day (s) China,Zhejiang
Hangzhou DayangChem Co., Ltd
Request For Quotation
View All Suppliers