aerobactin
CAS No.: 26198-65-2 Formula: C22H36N4O13 Molecular Weight: 564.54000
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aerobactin

CAS No.: 26198-65-2 Formula: C22H36N4O13 Molecular Weight: 564.54000
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Description

Aerobactin is a bacterial iron chelating agent (siderophore) found in E. coli. It is a virulence factor enabling E. coli to sequester iron in iron-poor environments such as the urinary tract.
Aerobactin is biosynthesized by the oxidation of lysine, catalyzed by the enzyme aerobactin synthase, which is then coupled to citric acid. The gene for this enzyme is found in the aerobactin operon, which is roughly 8 kilobases long and contains 5 or more genes in total.
Yersinia pestis contains genes relating to aerobactin, but they have been inactivated by a frameshift mutation, thus Y. pestis is no longer able to synthesize aerobactin.

Basic Info

Chemical Name aerobactin
Synonyms

CAS No. 26198-65-2
Molecular Formula C22H36N4O13
Molecular Weight 564.54000
PSA 271.41000
LogP -0.68110
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