propan-1-ol
CAS No.: 71-23-8 Formula: C3H8O Molecular Weight: 60.09500
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propan-1-ol

CAS No.: 71-23-8 Formula: C3H8O Molecular Weight: 60.09500
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Description

1-Propanol is a low molecular weight alcohol that is currently being investigated as an alternative fuel for direct methanol/oxygen fuel cells. 1-Propanol is also used as a coupling and dispersing agent in the pharmaceutical and chemicals industries.

Basic Info

Chemical Name propan-1-ol
Synonyms

Propanol-1; FEMA 2928; n-propylalcohol; propyl alcohol; Propanole; Propanoli; Propanolen; PROPANOL; albacol; Optal; 1-propyl alcohol; n-C3H7OH; 1-Propanol; Expand

CAS No. 71-23-8
Molecular Formula C3H8O
Molecular Weight 60.09500
PSA 20.23000
LogP 0.38870

Properties

Appearance & Physical State colourless liquid
Density 0.8
Boiling Point 97ºC
Melting Point -127ºC
Flash Point 15ºC
Refractive Index 1.384-1.386
Water Solubility soluble
Stability Stable. May form peroxides in contact with air. Incompatible with alkali metals, alkaline earths, aluminium, oxidizing agents, nitro compounds. Highly flammable. Vapour/air mixtures explosive.
Storage Condition Store at RT.
Vapor Density 2.1 (vs air)
Vapor Pressure 10 mm Hg ( 147 °C)

Safety Info

RTECS UH8225000
Hazard Class 3
Safety Statements S16-S24-S26-S39-S7
HS Code 2905121000
Packing Group II
WGK Germany 1
RIDADR UN 1274
Risk Statements R11; R41; R67
Hazard Codes F
Caution Statement P210; P261; P280; P305 + P351 + P338
Hazard Declaration H225; H318; H336
Symbol GHS02, GHS05, GHS07
Signal Word Danger
SDS 1.0 Expand

SDS 1.0

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SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name propan-1-ol

1.2 Other means of identification

Product number -
Other names Propanol-1

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Food additives -> Flavoring Agents
Uses advised against no data available

1.4 Supplier's details

Company XiXisys.com
Address XiXisys.com
Telephone XiXisys.com
Fax XiXisys.com

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Flammable liquids, Category 2

Serious eye damage, Category 1

Specific target organ toxicity – single exposure, Category 3

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Danger

Hazard statement(s)

H225 Highly flammable liquid and vapour

H318 Causes serious eye damage

H336 May cause drowsiness or dizziness

Precautionary statement(s)
Prevention

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.

P233 Keep container tightly closed.

P240 Ground and bond container and receiving equipment.

P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.

P242 Use non-sparking tools.

P243 Take action to prevent static discharges.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

Response

P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower].

P370+P378 In case of fire: Use ... to extinguish.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P310 Immediately call a POISON CENTER/doctor/…

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P312 Call a POISON CENTER/doctor/…if you feel unwell.

Storage

P403+P235 Store in a well-ventilated place. Keep cool.

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P405 Store locked up.

Disposal

P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
propan-1-ol propan-1-ol 71-23-8 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest.

In case of skin contact

Rinse and then wash skin with water and soap.

In case of eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

If swallowed

Rinse mouth. Refer for medical attention .

4.2 Most important symptoms/effects, acute and delayed

Contact with eyes is extremely irritating and may cause burns. Vapors irritate nose and throat. In high concentrations, may cause nausea, dizziness, headache, and stupor. (USCG, 1999)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Basic Treatment: Establish a patent airway. Suction if necessary Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . /Lower alcohols (1-3 Carbons) and related compounds/

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

To fight fire use alcohol foam, carbon dioxide, dry chemical.

5.2 Specific hazards arising from the chemical

Excerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. (ERG, 2016)

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

6.3 Methods and materials for containment and cleaning up

Absorb on paper. Evaporate on a glass or iron dish in hood. Burn the paper.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Fireproof. Separated from strong oxidants. Cool. Well closed. Keep in a well-ventilated room.Keep containers closed, store in cool, well ventilated place away from ignition sources.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 200 ppm (500 mg/cu m).

Recommended Exposure Limit: 15 Min Short-Term Exposure Limit: 250 ppm (625 mg/cu m) [skin].

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state colourless liquid
Colour Colorless liquid.
Odour Similar to ethanol
Melting point/ freezing point -127ºC
Boiling point or initial boiling point and boiling range 97°C(lit.)
Flammability Class IB Flammable Liquid: Fl.P. below 22.78°C and BP at or above 37.78°C.Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.
Lower and upper explosion limit / flammability limit Lower flammable limit: 2.2% by volume; Upper flammable limit: 13.7% by volume
Flash point 22°C
Auto-ignition temperature 371.11°C
Decomposition temperature no data available
pH no data available
Kinematic viscosity 2.256 cP @ 20°C
Solubility In water:soluble
Partition coefficient n-octanol/water (log value) no data available
Vapour pressure 10 mm Hg ( 147 °C)
Density and/or relative density 0.804g/mLat 25°C(lit.)
Relative vapour density 2.1 (vs air)
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

Dangerous upon exposure to heat or flame; can react vigorously with oxidizing materials.The vapour mixes well with air, explosive mixtures are easily formed.N-PROPANOL reacts with alkali metal, nitrides and strong reducing agents to give flammable and/or toxic gases. Reacts with oxoacids and carboxylic acids to form esters plus water. Converted by oxidizing agents to propanal or propionic acid. May initiate the polymerization of isocyanates and epoxides. Incompatible with strong oxidizing agents (NIOSH, 2016).

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Ignition occurs when potassium tert-butoxide reacts with ... n-propanol ...

10.6 Hazardous decomposition products

Toxic gases and vapors (such as carbon monoxide) may be released in a fire involving propyl alcohol.

11.Toxicological information

Acute toxicity

  • Oral: LD50 Rabbit oral 2.8 g/kg
  • Inhalation: no data available
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

A4: Not classifiable as a human carcinogen.

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: LC50 Pimephales promelas (fathead minnows) 4.48 g/l/96 hr (95% confidence limit 4.10-4.88 g/l); age 30 days old, water hardness 47.0 mg/l (CaCO3), temp 27.7°C, pH 7.40, dissolved oxygen 5.4 mg/l, alkalinity 43.0 mg/l (CaCO3), tank vol: 1.0 l, additions: 36 vol/day (flow-through bioassay)
  • Toxicity to daphnia and other aquatic invertebrates: no data available
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: n-Propanol is readily degraded in laboratory tests using activated sludges, sewage seeds, and wastewater inocula(1-4). In 1 day test using 500 mg/l n-propanol and activated sludge at 20°C, a 37% theoretical oxygen demand (ThOD) was obtained(1). Biodegradation of 3, 7, and 10 mg/l with filtered sewage seed in fresh water resulted in a 64% ThOD in 5 days and 75% ThOD in 20 days(2). n-Propanol was 99% removed using acclimated activated sludge at 20°C (71 mg COD/g-hr rate)(3). Biodegradation of n-propanol in fresh water, using a domestic and synthetic waste water seed, resulted in a 93% ThOD and 97% ThOD (in 5 day tests), respectively(4). Biodegradation of 3, 7, and 10 mg/l with filtered sewage seed in salt water resulted in a 43% ThOD in 5 days and 73% ThOD in 20 days(2).

12.3 Bioaccumulative potential

An estimated BCF of 3 was calculated for n-propanol(SRC), using a log Kow of 0.25(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

12.4 Mobility in soil

The Koc of n-propanol is estimated as 33(SRC), using a measured log Kow of 0.25(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that n-propanol is expected to have very high mobility in soil(SRC).

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN1274 IMDG: UN1274 IATA: UN1274

14.2 UN Proper Shipping Name

ADR/RID: n-PROPANOL (PROPYL ALCOHOL, NORMAL)
IMDG: n-PROPANOL (PROPYL ALCOHOL, NORMAL)
IATA: n-PROPANOL (PROPYL ALCOHOL, NORMAL)

14.3 Transport hazard class(es)

ADR/RID: 3 IMDG: 3 IATA: 3

14.4 Packing group, if applicable

ADR/RID: II IMDG: II IATA: II

14.5 Environmental hazards

ADR/RID: no IMDG: no IATA: no

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
propan-1-ol propan-1-ol 71-23-8 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

16.Other information

Information on revision

Creation Date Aug 16, 2017
Revision Date Aug 16, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
MSDS Expand
1H NMR : 90 MHz in CDCl3Expand

NMR Spectrum 1H NMR : 90 MHz in CDCl3

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C3 H8 O 0.04 ml : 0.5 ml CDCl3
1-propanol

Assign. Shift(ppm)
A 3.582
B 2.26
C 1.57
D 0.94

J(A,C)=6.6HZ.

IR : liquid filmExpand
Raman : 4880 A,100M,liquidExpand
Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
Oral LDLo - Lowest published lethal dose Human - woman 5700 mg/kg 1.Cardiac-other changes
2.Lungs, Thorax, or Respiration-other changes
Oral LD50 - Lethal dose, 50 percent kill Rodent - rat 1870 mg/kg 1.Details of toxic effects not reported other than lethal dose value
Inhalation LCLo - Lowest published lethal concentration Rodent - rat 4000 ppm/4H 1.Details of toxic effects not reported other than lethal dose value
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