Difluorochloromethane
CAS No.: 75-45-6 Formula: CHClF2 Molecular Weight: 86.46840
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Difluorochloromethane

CAS No.: 75-45-6 Formula: CHClF2 Molecular Weight: 86.46840
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Description

Chlorodifluoromethane or difluoromonochloromethane is a hydrochlorofluorocarbon (HCFC). This colorless gas is better known as HCFC-22, or R-22. It is commonly used as a propellant and refrigerant. These applications are being phased out in developed countries due to the compound's ozone depletion potential (ODP) and high global warming potential (GWP), although global use of R-22 continues to increase because of high demand in developing countries. R-22 is a versatile intermediate in industrial organofluorine chemistry, e.g. as a precursor to tetrafluoroethylene. R-22 cylinders are colored light green.

Basic Info

Chemical Name Difluorochloromethane
Synonyms

difluoromonochloromethane; HFA22; chlorodifluoromethane; Methane, chlorodifluoro-; 1-chloro-1,1-difluoro-methane; f22; difluoromethyl chloride; FC 22; CFC-22; monochloro-difluoromethane; FKW22; Expand

CAS No. 75-45-6
Molecular Formula CHClF2
Molecular Weight 86.46840
PSA 0.00000
LogP 1.44780

Properties

Appearance & Physical State Colourless gas
Density 1.17
Boiling Point -40.8ºC
Melting Point -146ºC
Refractive Index 1.264 (22ºC)
Water Solubility Slightly soluble
Stability Stable.
Storage Condition Keep container tightly closed. Keep away from heat, sparks and flames.

Safety Info

Hazard Class 2.2
Safety Statements S23-S59
HS Code 2903710000
RIDADR UN 1018/1973
Risk Statements R40; R59
Hazard Codes F
SDS 1.0 Expand

SDS 1.0

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SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Difluorochloromethane

1.2 Other means of identification

Product number -
Other names difluoromonochloromethane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Functional fluids (closed systems),Intermediates,Laboratory chemicals
Uses advised against no data available

1.4 Supplier's details

Company XiXisys.com
Address XiXisys.com
Telephone XiXisys.com
Fax XiXisys.com

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Gases under pressure: Liquefied gas

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Danger

Hazard statement(s)

H280 Contains gas under pressure; may explode if heated

Precautionary statement(s)
Prevention

none

Response

none

Storage

P410+P403 Protect from sunlight. Store in a well-ventilated place.

Disposal

none

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
Difluorochloromethane Difluorochloromethane 75-45-6 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.

In case of skin contact

ON FROSTBITE: rinse with plenty of water, do NOT remove clothes. Refer for medical attention .

In case of eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms/effects, acute and delayed

Inhalation at greater than 10% concentration in air may cause narcosis. Liquid may cause frostbite. (USCG, 1999)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Victims of freon inhalation require management for hypoxic, CNS anesthetic, & cardiac symptoms. Patients must be removed from the exposure environment, & high flow supplemental oxygen should be utilized. The respiratory system should be evaluated for injury, aspiration, or pulmonary edema & treated appropriately. CNS findings should be treated supportively. A calm environment with no physical exertion is imperative to avoid increasing endogenous adrenegic levels. Exogenous adrenergic drugs must not be used to avoid inducing sensitized myocardial dysrhythmias. Atropine is ineffective in treating bradyarrhythmias. For ventricular dysrhythmias, diphenylhydantoin & countershock may be effective. Cryogenic dermal injuries should be treated by water bath rewarming at 40-42°C until vasodilatory flush has returned. Elevation of the limb & standard frostbite management with late surgical debridement should be utilized. Ocular exposure requires irrigation & slit lamp evaluation for injury. /Freons/

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

If material involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible.

5.2 Specific hazards arising from the chemical

Special Hazards of Combustion Products: Decomposition gases are toxic and irritating. (USCG, 1999)

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Ventilation.

6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Fireproof. Cool. Ventilation along the floor.Store in a cool, well-ventilated area of low fire risk and out of direct sunlight. Protect cylinder and its fittings from physical damage. Storage in subsurface locations should be avoided. Close valve tightly after use and when empty.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

Recommended Exposure Limit: 10 Hour Time-Weighted Average: 1000 ppm (3500 mg/cu m).

Recommended Exposure Limit: 15 Minute Short-Term Exposure Limit: 1250 ppm (4375 mg/cu m).

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state Colourless gas
Colour Colorless gas ... [Note: Shipped as a liquefied compressed gas]
Odour Nearly odorless
Melting point/ freezing point -146ºC
Boiling point or initial boiling point and boiling range -40.8ºC
Flammability Nonflammable GasCombustible under specific conditions. Gives off irritating or toxic fumes (or gases) in a fire.
Lower and upper explosion limit / flammability limit no data available
Flash point no data available
Auto-ignition temperature Not flammable (USCG, 1999)
Decomposition temperature no data available
pH no data available
Kinematic viscosity 0.23 mN/sec/sq m at 25°C (liquid); 0.013 mN/sec/sq m at 25°C (gas)
Solubility In water:Slightly soluble
Partition coefficient n-octanol/water (log value) log Kow = 1.08
Vapour pressure 10991.42 mm Hg (USCG, 1999)
Density and/or relative density 1.17
Relative vapour density 3 (Air = 1)
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

The product is stable.

10.3 Possibility of hazardous reactions

Not flammable.The gas is heavier than air and may accumulate in lowered spaces causing a deficiency of oxygen.CHLORODIFLUOROMETHANE is incompatible with the following: Alkalis, alkaline earth metals (e.g., powdered aluminum, sodium, potassium, zinc) (NIOSH, 2016).

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

In a dichlorodifluoromethane system, frictional wear exposed fresh metal surfaces on an aluminum compressor impellor, causing an exothermic reaction which melted much of the impellor. Later tests showed similar results ... with ... chlorodifluoromethane ... .

10.6 Hazardous decomposition products

Decomposes on contact with hot surfaces or flames. This produces toxic and corrosive gases including hydrogen chloride, phosgene, hydrogen fluoride and carbonyl fluoride.

11.Toxicological information

Acute toxicity

  • Oral: no data available
  • Inhalation: LC50 Mouse inhalation 28 parts per hundred (pph)/20 minutes
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

Evaluation: There is inadequate evidence in humans for the carcinogenicity of chlorodifluoromethane. There is limited evidence in experimental animals for the carcinogenicity of chlorodifluoromethane. Overall evaluation: Chlorodifluoromethane is not classifiable as to its carcinogenicity in humans (Group 3).

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: no data available
  • Toxicity to daphnia and other aquatic invertebrates: no data available
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: Chlorodifluoromethane, present at 1.69 mg/L, reached 0% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 2 mg/L in the Japanese MITI test(1). The maximum oxidation rate measured for chlorodifluoromethane in aerobic soil microcosms incubated with methane and air to simulate the gas composition in landfill soil covers was 0.343 mg/g soil-hour(2).

12.3 Bioaccumulative potential

An estimated BCF of 2.4 was calculated in fish for chlorodifluoromethane(SRC), using a log Kow of 1.08(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

12.4 Mobility in soil

The Koc of chlorodifluoromethane is estimated as 8.6(SRC), using a log Kow of 1.08(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that chlorodifluoromethane is expected to have very high mobility in soil. However, since chlorodifluoromethane is a gas(4) under ambient conditions, most of the chemical released on soil will volatilize rapidly, effectively reducing the potential for leaching into groundwater(SRC).

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN1018 IMDG: UN1018 IATA: UN1018

14.2 UN Proper Shipping Name

ADR/RID: CHLORODIFLUOROMETHANE (REFRIGERANT GAS R 22)
IMDG: CHLORODIFLUOROMETHANE (REFRIGERANT GAS R 22)
IATA: CHLORODIFLUOROMETHANE (REFRIGERANT GAS R 22)

14.3 Transport hazard class(es)

ADR/RID: 2.2 IMDG: 2.2 IATA: 2.2

14.4 Packing group, if applicable

ADR/RID: unknown IMDG: unknown IATA: unknown

14.5 Environmental hazards

ADR/RID: no IMDG: no IATA: no

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
Difluorochloromethane Difluorochloromethane 75-45-6 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

16.Other information

Information on revision

Creation Date Aug 17, 2017
Revision Date Aug 17, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
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