Synthesis Route for 1083168-83-5

760207-87-2
5-Bromo-2-Methox...
73183-34-3
Bis(pinacolato)d...
~36%
1083168-83-5
2-methoxy-3-meth...

Reference:

VERTEX PHARMACEUTICALS INCORPORATED Patent: WO2008/141119 A2, 2008 ; Location in patent: Page/Page column 100-101 ; WO 2008/141119 A2