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N-methylpyrrolidin-2-one 872-50-4 MSDS

Section I.Chemical Product and Company Identification
    Chemical Name 1-Methyl-2-pyrrolidone
    Portland OR
    Synonym        N-Methylpyrrolidinone    
    Chemical Formula        C5H9NO    
    CAS Number        872-50-4    

Section II.        Composition and Information on Ingredients    
    Chemical Name        CAS Number Percent (%)        TLV/PEL        Toxicology Data    
    1-Methyl-2-pyrrolidone        872-50-4        Min. 99.0 Not available.        Rat LD50 (oral) 3914mg/kg    
    Rat LD50 (intravenous) 805mg/kg
    (GC)
    Rat LD50 (intraperitoneal)
    2472mg/kg

Section III. Hazards Identification
    Acute Health Effects        Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system. Inflammation of the    
    eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening,
    or, occasionally, blistering. Follow safe industrial hygiene practices and always wear proper protective equipment when
    handling this compound.
    CARCINOGENIC EFFECTS : Not available.
    Chronic Health Effects
    MUTAGENIC EFFECTS : Not available.
    TERATOGENIC EFFECTS : Not available.
    DEVELOPMENTAL TOXICITY: Not available.
    There is no known effect from chronic exposure to this product. Repeated or prolonged exposure to this compound is
    not known to aggravate existing medical conditions.

Section IV.        First Aid Measures    
    Eye Contact        Check for and remove any contact lenses. IMMEDIATELY flush eyes with running water for at least 15 minutes, keeping    
    eyelids open. COLD water may be used. DO NOT use an eye ointment. Flush eyes with running water for a minimum of
    15 minutes, occasionally lifting the upper and lower eyelids. Seek medical attention. Treat symptomatically and
    supportively.
    Skin Contact        If the chemical gets spilled on a clothed portion of the body, remove the contaminated clothes as quickly as possible,    
    protecting your own hands and body. Place the victim under a deluge shower. If the chemical touches the victim's
    exposed skin, such as the hands: Gently and thoroughly wash the contaminated skin with running water and non-abrasive
    soap. Be particularly careful to clean folds, crevices, creases and groin. COLD water may be used. Cover the irritated
    skin with an emollient. Seek medical attention. Treat symptomatically and supportively. Wash any contaminated clothing
    before reusing.
    If the victim is not breathing, perform artificial respiration. Loosen tight clothing such as a collar, tie, belt or waistband. If
    Inhalation
    breathing is difficult, oxygen can be administered. Seek medical attention. Treat symptomatically and supportively.
    Ingestion        INDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not reenter the mouth and throat.    
    Loosen tight clothing such as a collar, tie, belt, or waistband. If the victim is not breathing, administer artificial respiration.
    Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic material
    was ingested; the absence of such signs, however, is not conclusive. Seek immediate medical attention and, if possible,
    show the chemical label. Treat symptomatically and supportively.

Section V. Fire and Explosion Data
    269°C (516.2°F)
    Combustible.        Auto-Ignition    
    Flammability
    Flammable Limits
    Flash Points        LOWER: 1.3% UPPER: 9.5%    
    86°C (186.8°F).
    Combustion Products        These products are toxic carbon oxides (CO, CO 2), nitrogen oxides (NO, NO2).    
    Fire Hazards
    No specific information is available regarding the flammability of this compound in the presence of various materials.
    Continued on Next Page
    872-50-4erNINGS(Intern
    Risks of explosion of the product in presence of mechanical impact: Not available.
    Explosion Hazards
    Risks of explosion of the product in presence of static discharge: Not available.
    No additional information is available regarding the risks of explosion.
    Fire Fighting Media
    SMALL FIRE: Use DRY chemicals, CO 2, water spray or foam.
    LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet.
    and Instructions

Section VI.        Accidental Release Measures    
    Spill Cleanup
    Irritating material. Combustible material.
    Keep away from heat and sources of ignition. Mechanical exhaust required. Stop leak if without risk. Finish cleaning the
    Instructions
    spill by rinsing any contaminated surfaces with copious amounts of water. Consult federal, state, and/or local authorities
    for assistance on disposal.

Section VII. Handling and Storage
    Handling and Storage        IRRITANT. COMBUSTIBLE. HYGROSCOPIC. STORE UNDER NITROGEN. Keep away from heat and sources of    
    ignition. Mechanical exhaust required. When not in use, tightly seal the container and store in a dry, cool place. Avoid
    Information
    excessive heat and light. DO NOT ingest. Do not breathe gas, fumes, vapor or spray. In case of insufficient ventilation,
    wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label.
    Treat symptomatically and supportively. Avoid contact with skin and eyes.
    Always store away from incompatible compounds such as oxidizing agents, acids.

Section VIII. Exposure Controls/Personal Protection
    Engineering Controls        Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their    
    respective threshold limit value. Ensure that eyewash station and safety shower is proximal to the work-station location.
    Personal Protection        Splash goggles. Lab coat. Vapor respirator. Boots. Gloves. A MSHA/NIOSH approved respirator must be used to avoid    
    inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling
    this product.
    Exposure Limits        Not available.    

Section IX. Physical and Chemical Properties
    Solubility
    Physical state @ 20°C        Colorless liquid.        Soluble in cold water, hot water, ether and    
    acetone.
    1.03
    Specific Gravity
    Molecular Weight        99.13        Partition Coefficient        Not available.    
    Boiling Point        202°C (395.6°F)        Vapor Pressure        0.29 mm of Hg (@ 20°C)    
    Melting Point        -23°C (-9.4°F)        Vapor Density        3.4 (Air = 1) @ 20°C    
    Not available.        Volatility        Not available.    
    Refractive Index
    Critical Temperature        Not available.        Odor        Not available.    
    Viscosity        Not available.        Taste        Not available.    

Section X.        Stability and Reactivity Data    
    Stability    
This material is stable if stored under proper conditions. (See Section VII for instructions)    
    Conditions of Instability        Avoid excessive heat and light. Hygroscopic; keep container tightly closed. Store under nitrogen.    
    Incompatibilities
    Highly reactive with oxidizing agents, acids.

Section XI. Toxicological Information
    RTECS Number        UY5790000    
    Eye contact. Inhalation. Ingestion. Skin contact.
    Routes of Exposure
    Toxicity Data        Rat LD50 (oral) 3914mg/kg    
    Rat LD50 (intravenous) 805mg/kg
    Rat LD50 (intraperitoneal) 2472mg/kg
    Chronic Toxic Effects        CARCINOGENIC EFFECTS : Not available.    
    MUTAGENIC EFFECTS : Not available.
    TERATOGENIC EFFECTS : Not available.
    DEVELOPMENTAL TOXICITY: Not available.
    There is no known effect from chronic exposure to this product. Repeated or prolonged exposure to this compound is not known
    to aggravate existing medical conditions.
    Acute Toxic Effects        Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system. Inflammation of the eye is    
    characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or,
    occasionally, blistering. Follow safe industrial hygiene practices and always wear proper protective equipment when handling
    this compound.
    Continued on Next Page
    1-Methyl-2-pyrrolidone

Section XII.        Ecological Information    
    Ecotoxicity        Not available.    
    1-Methyl-2-pyrrolidinone is used as a solvent in a wide variety of commercial applications. It may be released to the
    Environmental Fate
    environment as a fugitive emission during its production and use. 1-Methyl-2-pyrrolidinone may be a naturally occurring
    compound. If released to soil, 1-methyl-2-pyrrolidinone has the potential to biodegrade under aerobic conditions. It is
    expected to display very high mobility in soil. 1-Methyl-2-pyrrolidinone may slowly volatilize from dry soil to the
    atmosphere, but it is not expected to significantly volatilize from moist soil. If released to water, screening studies indicate
    that 1-methyl-2-pyrrolidinone will biodegrade under aerobic conditions after a short lag period. A calculated
    bioconcentration factor of 0.16 indicates that 1-methyl-2-pyrrolidinone is not expected to significantly bioconcentrate in fish
    and aquatic organisms nor is it expected to significantly adsorb to sediment or suspended organic matter. An estimated
    Henry's Law constant of 1.56X10E-8 atm-cu m/mole at 25 deg indicates that 1-methyl-2-pyrrolidinone is not expected to
    significantly volatilize from water to the atmosphere. The estimated half-life for volatilization of 1-methyl-2-pyrrolidinone
    from a model river is 2335 days. If released to the atmosphere, 1-methyl-2-pyrrolidinone is expected to undergo a
    gas-phase reaction with photochemically produced hydroxyl radicals with an estimated half-life of 5.2 hrs. It may undergo
    atmospheric removal by wet deposition processes. Occupational exposure to 1-methyl-2-pyrrolidinone may occur by
    inhalation or dermal contact during its production and use. The general population may be exposed to
    1-methyl-2-pyyrolidinone by the ingestion of foods in which it is contained or by the ingestion of contaminated drinking
    water. (HSDB)

Section XIII. Disposal Considerations
    Waste Disposal        Recycle to process, if possible. Consult your local or regional authorities. You may be able to dissolve or mix material with    
    a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all
    federal, state, and local regulations when disposing of this substance.

Section XIV. Transport Information
    DOT Classification        Not a DOT controlled material (United States).    
    PIN Number        Not applicable.    
    Proper Shipping Name        Not applicable.    
    Packing Group (PG)        Not applicable.    
    DOT Pictograms

Section XV. Other Regulatory Information and Pictograms
    TSCA Chemical Inventory        This product is ON the EPA Toxic Substance Control Act (TSCA) inventory.    
    (EPA)
    WHMIS Classification        WHMIS CLASS B-3: Combustible liquid with a flash point between 37.8°C (100°F) and 93.3°C (200°F).    
    WHMIS CLASS D-2B: Material causing other toxic effects (TOXIC).
    (Canada)
    EINECS Number (EEC) 212-828-1
    EEC Risk Statements
    R36/38- Irritating to eyes and skin.


SECTION 16 - ADDITIONAL INFORMATION
N/A

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