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oxytetracycline 79-57-2 MSDS
Name: Oxytetracycline Material Safety Data Sheet
Synonym: Hydrocyclin; Tetramine; Tetran Hydrochloride; Tetramycin Hydrochloride
CAS: 79-57-2
Section 1 - Chemical Product   MSDS Name:Oxytetracycline Material Safety Data Sheet
Synonym:Hydrocyclin; Tetramine; Tetran Hydrochloride; Tetramycin Hydrochloride

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
79-57-2 Oxytetracycline 100 201-212-8
Hazard Symbols: XN
Risk Phrases: 63

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Possible risk of harm to the unborn child.Light sensitive.
Potential Health Effects
Eye:
May cause eye irritation and possible burns.
Skin:
May cause skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause an anticoagulant effect in the blood.
Inhalation:
Dust is irritating to the respiratory tract. May cause respiratory tract irritation.
Chronic:
May cause reproductive and fetal effects. Chronic exposure may cause blood effects.

Section 4 - FIRST AID MEASURES
  Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Substance is noncombustible. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. Use water spray to reduce vapors or divert vapor cloud drift.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Store protected from light.
Storage:
Store in a cool, dry place. Do not store in direct sunlight. Keep from freezing. Keep container closed when not in use. Store below 40C.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels.
Exposure Limits CAS# 79-57-2: Russia: 0.1 mg/m3 TWA Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions. A NIOSH/MSHA approved air purifying dust or mist respirator or European Standard EN 149.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Crystalline powder
Color: pale yellow to tan
Odor: None reported.
pH: 6.5 approx.
Vapor Pressure: Negligible.
Viscosity: Negligible.
Boiling Point: Decomposes
Freezing/Melting Point: 183 deg C dec
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: N/A
Explosion Limits, upper: N/A
Decomposition Temperature: > 183 deg C
Solubility in water: Slightly soluble.
Specific Gravity/Density: 1.634@ 20C
Molecular Formula: C22H24N2O9
Molecular Weight: 460.39

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures. Darkens and decomposes on exposure to light.
Conditions to Avoid:
Incompatible materials, light, acids, strong oxidants.
Incompatibilities with Other Materials:
Acidic conditions, strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 79-57-2: QI7875000 LD50/LC50:
CAS# 79-57-2: Oral, mouse: LD50 = 2240 mg/kg; Oral, mouse: LD50 = 5706 mg/kg; Oral, rat: LD50 = 4800 mg/kg; Oral, rat: LD50 = 5063 mg/kg.
Carcinogenicity:
Oxytetracycline - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
 

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 63 Possible risk of harm to the unborn child.
Safety Phrases:
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 79-57-2: No information available.
Canada
CAS# 79-57-2 is listed on Canada's DSL List.
CAS# 79-57-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 79-57-2 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

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