|Name:||Phosgene solution in toluene Material Safety Data Sheet|
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 11 26/27/28 63 67
Section 3 - HAZARDS IDENTIFICATION
Highly flammable. Very toxic by inhalation, in contact with skin and if swallowed. Possible risk of harm to the unborn child. Vapours may cause drowsiness and dizziness.
Potential Health Effects
Causes eye irritation. May result in corneal injury. Vapors may cause eye irritation.
May cause skin irritation. May be absorbed through the skin in harmful amounts. Prolonged and/or repeated contact may cause irritation and/or dermatitis.
Aspiration hazard. May cause irritation of the digestive tract. May cause effects similar to those for inhalation exposure. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal.
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. Inhalation of vapor may cause respiratory tract irritation.
May cause liver and kidney damage. May cause heart disturbances, possibly leading to cardiac arrest and death.
Chronic exposure to organic solvents has been associated with various neurotoxic effects including permanent brain and nervous system damage. Prolonged or repeated skin contact may cause dermatitis. May cause cardiac sensitization and severe heart abnormalities.
Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed.
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Possible aspiration hazard. Get medical aid immediately.
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Causes cardiac sensitization to endogenous catelcholamines which may lead to cardiac arrhythmias. Do NOT use adrenergic agents such as epinephrine or pseudoepinephrine.
Section 5 - FIRE FIGHTING MEASURES
Containers can build up pressure if exposed to heat and/or fire. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Vapors can travel to a source of ignition and flash back. Flammable Liquid. Can release vapors that form explosive mixtures at temperatures above the flashpoint.
Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water.
Use dry chemical, carbon dioxide, or alcohol-resistant foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Avoid runoff into storm sewers and ditches which lead to waterways.
Scoop up with a nonsparking tool, then place into a suitable container for disposal. Use water spray to disperse the gas/vapor.
Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust. Provide ventilation.
Section 7 - HANDLING and STORAGE
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous.
Do not get on skin or in eyes. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 75-44-5: United Kingdom, WEL - TWA: 0.02 ppm TWA; 0.08 mg/m3 TWA United Kingdom, WEL - STEL: 0.06 ppm STEL; 0.25 mg/m3 STEL United States OSHA: 0.1 ppm TWA; 0.4 mg/m3 TWA Belgium - TWA: 0.02 ppm VLE; 0.08 mg/m3 VLE Belgium - STEL: 0.1 ppm VLE; 0.4 mg/m3 VLE France - VLE: 0.1 ppm VLE; 0.4 mg/m3 VLE Germany: 0.02 ppm TWA; 0.082 mg/m3 TWA Japan: 0.1 ppm OEL; 0.4 mg/m3 OEL Malaysia: 0.1 ppm TWA; 0.40 mg/m3 TWA Netherlands: 0.1 ppm STEL; 0.4 mg/m3 STEL Netherlands: 0.02 ppm MAC; 0.08 mg/m3 MAC Russia: 0.5 mg/m3 TWA Spain: 0.02 ppm VLA-ED; 0.08 mg/m3 VLA-ED Spain: 0.1 ppm VLA-EC; 0.4 mg/m3 VLA-EC CAS# 108-88-3: United Kingdom, WEL - TWA: 50 ppm TWA; 191 mg/m3 TWA United Kingdom, WEL - STEL: 150 ppm STEL; 574 mg/m3 STEL United States OSHA: 200 ppm TWA; 300 ppm Ceiling Belgium - TWA: 50 ppm VLE; 191 mg/m3 VLE France - VME: 100 ppm VME; 375 mg/m3 VME France - VLE: 150 ppm VLE; 550 mg/m3 VLE Germany: 50 ppm TWA; 190 mg/m3 TWA Germany: Skin absorber Japan: 50 ppm OEL; 188 mg/m3 OEL Malaysia: 50 ppm TWA; 188 mg/m3 TWA Netherlands: 40 ppm MAC; 150 mg/m3 MAC Russia: 50 mg/m3 TWA Spain: 50 ppm VLA-ED; 191 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Wear appropriate protective gloves to prevent skin exposure.
Wear appropriate protective clothing to prevent skin exposure.
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 111 deg C @ toluene
Freezing/Melting Point: 95 deg C @ toluene
Autoignition Temperature: Not applicable.
Flash Point: 4 deg C ( 39.20 deg F)
Explosion Limits, lower: 1.2
Explosion Limits, upper: 7
Decomposition Temperature: Not available.
Solubility in water: Insoluble in water.
Specific Gravity/Density: 0.91
Molecular Formula: Mixture
Molecular Weight: 0
Section 10 - STABILITY AND REACTIVITY
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat.
Incompatibilities with Other Materials:
Toluene is incompatible with bromine trifluoride, 1,3-dichloro-5,5-dimethyl-2,4-imidazolididione, dinitrogen tetroxide, concentrated nitric acid, nitric acid + sulfuric acid, silver perchlorate, strong oxidizers.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
CAS# 75-44-5: SY5600000 CAS# 108-88-3: XS5250000 LD50/LC50:
CAS# 108-88-3: Draize test, rabbit, eye: 870 ug Mild; Draize test, rabbit, eye: 2 mg/24H Severe; Draize test, rabbit, skin: 435 mg Mild; Draize test, rabbit, skin: 500 mg Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation, mouse: LC50 = 400 ppm/24H; Inhalation, mouse: LC50 = 30000 mg/m3/2H; Inhalation, mouse: LC50 = 19900 mg/m3/7H; Inhalation, mouse: LC50 = 10000 mg/m3; Inhalation, rat: LC50 = 49 gm/m3/4H; Oral, rat: LD50 = 636 mg/kg; Skin, rabbit: LD50 = 14100 uL/kg.
Phosgene - Not listed by ACGIH, IARC, or NTP.
Toluene - Not listed by ACGIH, IARC, or NTP.
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Cas# 108-88-3: LC50(96Hr.) = 24.0 mg/L Rainbow trout LC50(96Hr) = 24.0 mg/L Bluegill EC50(48Hr) = 310-313 mg/L Photobacterium phosphoreum
Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.
Section 14 - TRANSPORT INFORMATION
No information available.
No information available.
No information available.
USA RQ: CAS# 75-44-5: 10 lb final RQ; 4.54 kg final RQ
USA RQ: CAS# 108-88-3: 1000 lb final RQ; 454 kg final RQ
Section 15 - REGULATORY INFORMATION
European Labeling in Accordance with EC Directives
Hazard Symbols: T+ F
R 11 Highly flammable.
R 26/27/28 Very toxic by inhalation, in contact with
skin and if swallowed.
R 63 Possible risk of harm to the unborn child.
R 67 Vapours may cause drowsiness and dizziness.
S 16 Keep away from sources of ignition - No
S 29 Do not empty into drains.
S 33 Take precautionary measures against static
WGK (Water Danger/Protection)
CAS# 75-44-5: 2
CAS# 108-88-3: 2
CAS# 75-44-5 is listed on Canada's DSL List.
CAS# 108-88-3 is listed on Canada's DSL List.
CAS# 75-44-5 is listed on Canada's Ingredient Disclosure List.
CAS# 108-88-3 is listed on Canada's Ingredient Disclosure List.
CAS# 75-44-5 is listed on the TSCA inventory.
CAS# 108-88-3 is listed on the TSCA inventory.
SECTION 16 - ADDITIONAL INFORMATION