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mestranol
CAS No.: 72-33-3
Synonyms:
Formula: C21H26O2
Exact Mass: 310.19300
Molecular Weight: 310.43000
PSA: 29.46000
LogP: 3.91560
Reference Price: $4,952/kg Inquiry Now
mestranol 72-33-3 MSDS
Name: Ethynylestradiol 3-methyl ether 97% Material Safety Data Sheet
Synonym: 3-Methoxyethynylestradiol; 3-Methoxy-17-alpha-ethynylestradiol; 17-Ethynyloestradiol 3-methyl ether
CAS: 72-33-3
Section 1 - Chemical Product   MSDS Name:Ethynylestradiol 3-methyl ether 97% Material Safety Data Sheet
Synonym:3-Methoxyethynylestradiol; 3-Methoxy-17-alpha-ethynylestradiol; 17-Ethynyloestradiol 3-methyl ether

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
72-33-3 Ethynylestradiol 3-methyl ether 97% 200-777-8
Hazard Symbols: XN
Risk Phrases: 33

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Danger of cumulative effects.Cancer suspect agent.
Potential Health Effects
Eye:
May cause mechanical irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause nausea and vomiting.
Inhalation:
May cause respiratory tract irritation.
Chronic:
May cause cancer according to animal studies. Adverse reproductive effects have been reported in humans. Cancer suspect agent.

Section 4 - FIRST AID MEASURES
  Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Call a poison control center. If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions. Provide ventilation.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Use only in a chemical fume hood.
Storage:
Do not store in direct sunlight. Store in a tightly closed container. Hormones and antibiotics room. Store in a cool, dry area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 72-33-3: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Powder
Color: white
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 153 - 155 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: slightly soluble in methanol
Specific Gravity/Density: Not available.
Molecular Formula: C21H26O2
Molecular Weight: 310.1808

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, light.
Incompatibilities with Other Materials:
Strong oxidizing agents, acid anhydrides.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 72-33-3: RC8960000 LD50/LC50:
CAS# 72-33-3: Oral, mouse: LD50 = >10 gm/kg; Oral, rat: LD50 = >10 gm/kg.
Carcinogenicity:
Ethynylestradiol 3-methyl ether - California: carcinogen, initial date 4/1/88 Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
 

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 33 Danger of cumulative effects.
Safety Phrases:
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 72-33-3: 2
Canada
CAS# 72-33-3 is listed on Canada's DSL List.
CAS# 72-33-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 72-33-3 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

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