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flucythrinate 70124-77-5 MSDS

  Product identifiers
    Product name        : Flucythrinate    
    CAS-No.        : 70124-77-5    
  Relevant identified uses of the substance or mixture and uses advised against
    Identified uses        : Laboratory chemicals, Manufacture of substances    

  Classification of the substance or mixture
  Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
    Acute toxicity, Oral (Category 3)
    Acute toxicity, Inhalation (Category 3)
    Acute toxicity, Dermal (Category 4)
    Acute aquatic toxicity (Category 1)
    Chronic aquatic toxicity (Category 1)
  Classification according to EU Directives 67/548/EEC or 1999/45/EC
    Harmful by inhalation and in contact with skin. Toxic if swallowed. Very toxic to aquatic organisms, may
    cause long-term adverse effects in the aquatic environment.
  Label elements
  Labelling according Regulation (EC) No 1272/2008 [CLP]
    Signal word        Danger    
    Hazard statement(s)
    H301 + H331        Toxic if swallowed or if inhaled    
    H312        Harmful in contact with skin.    
    H410        Very toxic to aquatic life with long lasting effects.    
    Precautionary statement(s)
    P261        Avoid breathing vapours.    
    P273        Avoid release to the environment.    
    P280        Wear protective gloves/ protective clothing.    
    P301 + P310        IF SWALLOWED: Immediately call a POISON CENTER or doctor/    
    P311        Call a POISON CENTER or doctor/ physician.    
    P501        Dispose of contents/ container to an approved waste disposal plant.    
    Supplemental Hazard        none    
  According to European Directive 67/548/EEC as amended.
    Hazard symbol(s)
    R20/21        Harmful by inhalation and in contact with skin.    
    R25        Toxic if swallowed.    
    R50/53        Very toxic to aquatic organisms, may cause long-term adverse effects in    
    the aquatic environment.
    S36/37        Wear suitable protective clothing and gloves.    
    S45        In case of accident or if you feel unwell, seek medical advice immediately    
    (show the label where possible).
    S60        This material and its container must be disposed of as hazardous waste.    
    S61        Avoid release to the environment. Refer to special instructions/ Safety    
    data sheets.
  Other hazards - none

    : α-Cyano-3-phenoxybenzyl 4-difluoromethoxy-α-isopropylphenylacetate
    Formula        : C26H23F2NO4    
    Molecular Weight        : 451,46 g/mol    
    Component        Concentration    
    CAS-No.        70124-77-5        -    
    EC-No.        274-322-7    

  Description of first aid measures
  General advice
    Consult a physician. Show this safety data sheet to the doctor in attendance.
  If inhaled
    If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
  In case of skin contact
    Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
  In case of eye contact
    Flush eyes with water as a precaution.
  If swallowed
    Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
  Most important symptoms and effects, both acute and delayed
    tachycardia, hypertension, nervousness, Tremors, Palpitation, Nausea, Vomiting, To the best of our
    knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
  Indication of any immediate medical attention and special treatment needed
    no data available

  Extinguishing media
  Suitable extinguishing media
    Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
  Special hazards arising from the substance or mixture
    Carbon oxides, nitrogen oxides (NOx), Hydrogen fluoride
  Advice for firefighters
    Wear self contained breathing apparatus for fire fighting if necessary.
  Further information
    no data available

  Personal precautions, protective equipment and emergency procedures
    Wear respiratory protection. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate
    personnel to safe areas.
  Environmental precautions
    Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
    environment must be avoided.
  Methods and materials for containment and cleaning up
    Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed
    containers for disposal.
  Reference to other sections
    For disposal see section 13.

  Precautions for safe handling
    Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.
  Conditions for safe storage, including any incompatibilities
    Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are
    opened must be carefully resealed and kept upright to prevent leakage.
    Recommended storage temperature: 2 - 8 °C
  Specific end use(s)
    no data available

  Control parameters
  Components with workplace control parameters
  Exposure controls
  Appropriate engineering controls
    Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling
    the product.
  Personal protective equipment
  Eye/face protection
    Face shield and safety glasses Use equipment for eye protection tested and approved under
    appropriate government standards such as NIOSH (US) or EN 166(EU).
  Skin protection
    Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
    (without touching glove's outer surface) to avoid skin contact with this product. Dispose of
    contaminated gloves after use in accordance with applicable laws and good laboratory practices.
    Wash and dry hands.
    The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
    the standard EN 374 derived from it.
  Body Protection
    Complete suit protecting against chemicals, The type of protective equipment must be selected
    according to the concentration and amount of the dangerous substance at the specific workplace.
  Respiratory protection
    Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator
    with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup
    to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air
    respirator. Use respirators and components tested and approved under appropriate government
    standards such as NIOSH (US) or CEN (EU).

  Information on basic physical and chemical properties
    a) Appearance        Form: liquid    
    Colour: colourless
    b) Odour        no data available    
    c) Odour Threshold        no data available    
    d) pH        no data available    
    e) Melting point/freezing        no data available    
    f) Initial boiling point and 108 °C at 0,47 hPa
    boiling range
    g) Flash point        no data available    
    h) Evaporation rate        no data available    
    i) Flammability (solid, gas) no data available
    j) Upper/lower        no data available    
    flammability or
    explosive limits
    k) Vapour pressure        no data available    
    l) Vapour density        no data available    
    m) Relative density        1,189 g/cm3 at 22 °C    
    n) Water solubility        no data available    
    o) Partition coefficient: n- log Pow: 6,2
    p) Auto-ignition        no data available    
    q) Decomposition        no data available    
    r) Viscosity        no data available    
    s) Explosive properties        no data available    
    t) Oxidizing properties        no data available    
  Other safety information
    no data available

    no data available
  Chemical stability
    no data available
  Possibility of hazardous reactions
    no data available
  Conditions to avoid
    no data available
  Incompatible materials
    Strong oxidizing agents
  Hazardous decomposition products
    Other decomposition products - no data available

  Information on toxicological effects
  Acute toxicity
    LD50 Oral - rat - 67 mg/kg
    LC50 Inhalation - rat - 4 h - 4.850 mg/m3
    LD50 Dermal - rabbit - > 1.000 mg/kg
  Skin corrosion/irritation
    no data available
  Serious eye damage/eye irritation
    no data available
  Respiratory or skin sensitization
    Prolonged or repeated exposure may cause allergic reactions in certain sensitive individuals.
  Germ cell mutagenicity
    no data available
    IARC:        No component of this product present at levels greater than or equal to 0.1% is identified as    
    probable, possible or confirmed human carcinogen by IARC.
  Reproductive toxicity
    no data available
  Specific target organ toxicity - single exposure
    no data available
  Specific target organ toxicity - repeated exposure
    no data available
  Aspiration hazard
    no data available
  Potential health effects
  Inhalation        Toxic if inhaled. May cause respiratory tract irritation.    
  Ingestion        Toxic if swallowed.    
    Harmful if absorbed through skin. May cause skin irritation.
  Eyes        May cause eye irritation.    
  Signs and Symptoms of Exposure
    tachycardia, hypertension, nervousness, Tremors, Palpitation, Nausea, Vomiting, To the best of our
    knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
  Additional Information
    RTECS: CY1578620

    Toxicity to fish        LC50 - Pimephales promelas (fathead minnow) - 0,190 mg/l - 96,0 h    
  Persistence and degradability
  Bioaccumulative potential
    Bioaccumulation        Cyprinodon variegatus (sheepshead minnow) - 28 d -0,27 µg/l    
    Bioconcentration factor (BCF): < 1.800
  Mobility in soil
    no data available
  Results of PBT and vPvB assessment
    no data available
  Other adverse effects
    Very toxic to aquatic life.

  Waste treatment methods
    Offer surplus and non-recyclable solutions to a licensed disposal company.
  Contaminated packaging
    Dispose of as unused product.

  UN number
    ADR/RID: 2810        IMDG: 2810        IATA: 2810    
  UN proper shipping name
    ADR/RID: TOXIC LIQUID, ORGANIC, N.O.S. (Flucythrinate)
    IMDG: TOXIC LIQUID, ORGANIC, N.O.S. (Flucythrinate)
    IATA:        Toxic liquid, organic, n.o.s. (Flucythrinate)    
  Transport hazard class(es)
    ADR/RID: 6.1        IMDG: 6.1        IATA: 6.1    
  Packaging group
    ADR/RID: III        IMDG: III        IATA: III    
  Environmental hazards
    ADR/RID: yes        IMDG Marine Pollutant: yes        IATA: no    
  Special precautions for user
    no data available

    This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
  Safety, health and environmental regulations/legislation specific for the substance or mixture
    no data available
  Chemical Safety Assessment
    no data available

  Further information
    Copyright 2012 Co. LLC. License granted to make unlimited paper copies for internal use
    The above information is believed to be correct but does not purport to be all inclusive and shall be
    used only as a guide. The information in this document is based on the present state of our knowledge
    and is applicable to the product with regard to appropriate safety precautions. It does not represent any
    guarantee of the properties of the product. Corporation and its Affiliates shall not be held
    liable for any damage resulting from handling or from contact with the above product. See
     and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.

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