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Triamcinolone diacetate
CAS No.: 67-78-7
Formula: C25H31FO8
Exact Mass: 478.20000
Molecular Weight: 478.50700
PSA: 127.20000
LogP: 1.76210
Reference Price: $2,047/kg Inquiry Now
Triamcinolone diacetate 67-78-7 MSDS

Section 1. Chemical Product and Company Identification
    Triamcinolone diacetate
    Common Name/
    Trade Name
    Triamcinolone diacetate

Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at    
    least 15 minutes. Get medical attention if irritation occurs.
    Skin Contact        Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.    
    Serious Skin Contact        Not available.    
    Inhalation        If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get    
    medical attention.
    Serious Inhalation        Not available.    
    Ingestion        Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an    
    unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
    clothing such as a collar, tie, belt or waistband.
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Flash Points        Not available.    
    Flammable Limits        Not available.    
    Products of Combustion        These products are carbon oxides (CO, CO2), halogenated compounds.    
    Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
    Various Substances
    Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
    Risks of explosion of the product in presence of static discharge: Not available.
    of Various Substances
    SMALL FIRE: Use DRY chemical powder.
    Fire Fighting Media
    and Instructions        LARGE FIRE: Use water spray, fog or foam. Do not use water jet.    
    As with most organic solids, fire is possible at elevated temperatures.
    Special Remarks on
    When heated to decomposition it emits acrid smoke and toxic fumes of Fluorine.
    Fire Hazards
    Special Remarks on Explosion Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust
    Hazards        explosion hazard.    

Section 6. Accidental Release Measures
    Small Spill        Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by    
    spreading water on the contaminated surface and dispose of according to local and regional authority
    Large Spill        Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water    
    on the contaminated surface and allow to evacuate through the sanitary system.
    Triamcinolone diacetate

Section 7. Handling and Storage
    Precautions        Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not    
    breathe dust.
    Storage        Keep container tightly closed. Keep container in a cool, well-ventilated area.    

Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below    
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
    airborne contaminants below the exposure limit.
    Personal Protection
    Safety glasses. Lab coat. Dust respirator. Use a dust respirator if ventilation is inadequate and is handling of
    material creates visible dust clouds. Be sure to use an approved/certified respirator or equivalent. Gloves.
    Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
    a Large Spill        to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist    
    BEFORE handling this product.
    Exposure Limits        Not available.    

Section 9. Physical and Chemical Properties
    Physical state and appearance Solid. (Powdered solid. Crystalline powder.)        Odor        Slight.    
    Taste        Not available.    
    Molecular Weight        478.51 g/mole    
    Color        White. Off-white.    
    pH (1% soln/water)        Not applicable.    
    Boiling Point        Not available.    
    Melting Point        186°C (366.8°F) - 188 C.    
    Critical Temperature        Not available.    
    Not available.
    Specific Gravity
    Vapor Pressure        Not applicable.    
    Vapor Density        Not available.    
    Volatility        Not available.    
    Odor Threshold        Not available.    
    Not available.
    Water/Oil Dist. Coeff.
    Ionicity (in Water)        Not available.    
    Not available.
    Dispersion Properties
    Solubility        Insoluble in cold water, hot water.    

Section 10. Stability and Reactivity Data
    Stability        The product is stable.    
    Not available.
    Instability Temperature
    Conditions of Instability        Excess heat    
    Incompatibility with various        Not available.    
    Corrosivity        Non-corrosive in presence of glass.    
    Triamcinolone diacetate
    Special Remarks on        Not available.    
    Special Remarks on        Not available.    
    Polymerization        Will not occur.    

Section 11. Toxicological Information
    Routes of Entry        Inhalation. Ingestion.    
    Toxicity to Animals        LD50: Not available.    
    LC50: Not available.
    Chronic Effects on Humans Not available.
    Other Toxic Effects on        Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.    
    Special Remarks on        Not available.    
    Toxicity to Animals
    Special Remarks on
    May cause adverse reproductive effects and birth defects (teratogenic) based on animal test data
    Chronic Effects on Humans
    Special Remarks on other        Acute Potential Health Effects:    
    Toxic Effects on Humans        Skin: May cause skin irritation with itching, erythema, folliculitis, pustules, pyoderma, vesiculation, hyperesthesia.    
    Eyes: Dust may cause eye irritation.
    Inhalation: Dust may cause respiratory tract irritation.
    Ingestion: May cause gastrointestinal tract irritation with indigestion. Ingestion as well as if orally-inhaled may
    cause adverse effects which may include decreased or blurred vision, frequent urination, increased thirst, loss or
    increase of appetite, nervousness or restlessness, and trouble sleeping, hypertension, electrolyte imbalances due
    to sodiuim/fluid retention, hyperglycemia and glycosuria.
    Note: Possible allergic reaction to material if inhaled, ingested or in contact with skin.
    Chronic Potential Health Effects: Possible hypersensitization, acne or other skin problems, hip or shoulder pain,
    fullness in face, swelling of feet or lower legs, menstrual irregularities, hirsutism, hypopigmentation, nausea,
    vomiting, irregular heartbeat, muscle cramps, weakness, osteoporisis, increased susceptibilitiy to infection,
    psychosis, and eye problems (cataracts, glaucoma with possible damage to the optic nerve).
    Prolonged or repeated skin contact may cause itching, allergic contact dermatitis.
    Medical Conditons Aggravated by Exposure: Hypersensitivity to this material or other corticosteroids; ocular
    herpes simples; active alcoholism; AIDS or HIV infection; heart disease or hypertension; diabetes mellitus;
    myasthenia gravis; impaired liver or kidney function; esophagitis; gastritis or peptic ulcer; chickenpox or measles
    (including recent exposure); tuberculosis; and system fungal infections.

Section 12. Ecological Information
    Not available.
    BOD5 and COD        Not available.    
    Products of Biodegradation        Possibly hazardous short term degradation products are not likely. However, long term degradation products may    
    Toxicity of the Products        The products of degradation are more toxic than the product itself.    
    of Biodegradation
    Special Remarks on the        Not available.    
    Products of Biodegradation
    Triamcinolone diacetate

Section 13. Disposal Considerations
    Waste Disposal        Waste must be disposed of in accordance with federal, state and local environmental    
    control regulations.

Section 14. Transport Information
    DOT Classification        Not a DOT controlled material (United States).    
    Not applicable.
    Not applicable.
    Special Provisions for
    DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
    No products were found.
    Federal and State
    California        California prop. 65: This product contains the following ingredients for which the State of California has found    
    to cause cancer which would require a warning under the statute: No products were found.
    Proposition 65
    California prop. 65: This product contains the following ingredients for which the State of California has found
    to cause birth defects which would require a warning under the statute: No products were found.
    Other Regulations        EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.    
    Other Classifications        WHMIS (Canada) Not controlled under WHMIS (Canada).    
    DSCL (EEC)        This product is not classified according Not applicable.    
    to the EU regulations.
    Health Hazard
    HMIS (U.S.A.)        1 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    1 0 Reactivity
    Specific hazard
    Personal Protection
    WHMIS (Canada)
    DSCL (Europe)
    TDG (Canada)
    Triamcinolone diacetate
    ADR (Europe)
    Protective Equipment
    Lab coat.
    Dust respirator. Be sure to use an
    approved/certified respirator or


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