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lidocaine hydrochloride monohydrate
CAS No.: 6108-05-0
Formula: C14H25ClN2O2
Exact Mass: 288.16000
Molecular Weight: 288.81400
PSA: 41.57000
LogP: 3.39440
Reference Price: $565/kg Inquiry Now
lidocaine hydrochloride monohydrate 6108-05-0 MSDS

Section 1. Chemical Product and Company Identification
    Lidocaine Hydrochloride monohydrate
    Common Name/
    Trade Name
    Lidocaine Hydrochloride monohydrate

Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for    
    at least 15 minutes. Cold water may be used. Get medical attention if irritation occurs.
    Skin Contact        Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation    
    develops. Cold water may be used.
    Serious Skin Contact        Not available.    
    Inhalation        If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.    
    Get medical attention.
    Serious Inhalation        Not available.    
    Ingestion        Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an    
    unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen
    tight clothing such as a collar, tie, belt or waistband.
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Flash Points        Not available.    
    Flammable Limits        Not available.    
    Products of Combustion        These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds.    
    Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
    Various Substances
    Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
    of Various Substances        Risks of explosion of the product in presence of static discharge: Not available.    
    Fire Fighting Media        SMALL FIRE: Use DRY chemical powder.    
    and Instructions        LARGE FIRE: Use water spray, fog or foam. Do not use water jet.    
    Special Remarks on        As with most organic solids, fire is possible at elevated temperatures    
    Fire Hazards
    Special Remarks on Explosion Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential
    Hazards        dust explosion hazard.    

Section 6. Accidental Release Measures
    Small Spill        Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by    
    spreading water on the contaminated surface and dispose of according to local and regional authority
    Large Spill        Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading    
    water on the contaminated surface and allow to evacuate through the sanitary system.

Section 7. Handling and Storage
    Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
    ingest. Do not breathe dust. Wear suitable protective clothing. If ingested, seek medical advice immediately
    and show the container or the label. Keep away from incompatibles such as oxidizing agents.
    Storage        Keep container tightly closed. Keep container in a cool, well-ventilated area.    
    Lidocaine Hydrochloride monohydrate

Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below    
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep
    exposure to airborne contaminants below the exposure limit.
    Personal Protection        Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.    
    Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be
    a Large Spill        used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a    
    specialist BEFORE handling this product.
    Exposure Limits        Not available.    

Section 9. Physical and Chemical Properties
    Physical state and appearance Solid. (crystalline powder.)        Odor        Odorless.    
    Taste        Not available.    
    Molecular Weight        288.81 g/mole    
    Color        White.    
    pH (1% soln/water)        Not available.    
    Not available.
    Boiling Point
    Melting Point        74°C (165.2°F)    
    Critical Temperature        Not available.    
    Specific Gravity        Not available.    
    Vapor Pressure        Not applicable.    
    Vapor Density        Not available.    
    Volatility        Not available.    
    Not available.
    Odor Threshold
    Water/Oil Dist. Coeff.        Not available.    
    Ionicity (in Water)        Not available.    
    Dispersion Properties        See solubility in water.    
    Solubility        Easily soluble in cold water.    
    Insoluble in diethyl ether.
    Soluble in benzene, ethanol, chloroform

Section 10. Stability and Reactivity Data
    The product is stable.
    Instability Temperature        Not available.    
    Excess heat, incompatible materials
    Conditions of Instability
    Incompatibility with various        Reactive with oxidizing agents.    
    Corrosivity        Non-corrosive in presence of glass.    
    Special Remarks on        Not available.    
    Special Remarks on        Not available.    
    Polymerization        Will not occur.    
    Lidocaine Hydrochloride monohydrate

Section 11. Toxicological Information
    Routes of Entry        Absorbed through skin. Inhalation. Ingestion.    
    Toxicity to Animals        Acute oral toxicity (LD50): 292 mg/kg [Mouse].    
    Chronic Effects on Humans        Causes damage to the following organs: the nervous system.    
    May cause damage to the following organs: cardiovascular system, central nervous system (CNS).
    Other Toxic Effects on        Hazardous in case of ingestion.    
    Humans        Slightly hazardous in case of skin contact (irritant), of inhalation.    
    Special Remarks on        Not available.    
    Toxicity to Animals
    Special Remarks on
    May cause adverse reproductive effects and birth defects (teratogenic) based on animal test data
    Chronic Effects on Humans
    Special Remarks on other        Aute Potential Health Effects:    
    Toxic Effects on Humans        Skin: May cause skin irritation and numbness (anesthetic effect). When applied to the skin, it produces an    
    anesthetic effect by blocking the signals at the nerve endings of the skin. when compounded with an ointment
    and applied topically, It may be absorbed by the skin cause systemic effects similar to that of ingestion.
    Eyes: May cause eye irritation and numbness.
    Inhalation: Dust may cause respiratory tract irritation and numbness.
    Ingestion: Harmful of swallowed. May cause abdominal discomfort, nausea, vomiting. May affect
    behavior/central nervous system (convulsions/seizures, drowsiness, lightheadedness, dizziness, confusion,
    disorientation, muscle twitching or trembling, somnolence, unusual excitement, unusual tiredness or
    weakness, nervousness, restlessness), cardiovascular system (hypotension, change in heart rate with
    possibe cardiac arrest). May also cause shortness of breath or trouble breathing, ringing or buzzing in the
    ears, feeling hot, cold or numb, increased sweating, blurred or double vision.
    Chronic Potential Health Effects:
    Skin: May cause allergic skin reaction with rash, hives, swelling, or abnormal sensation at the site of
    Ingestion/Inhalation: It is rare, but it may cause allergic reaction with cough, difficulty swallowing or tongue
    swelling, dizziness or fainting, hives or swelling of the eyelids, face or lips; itching or skin rash, stuffy nose,
    chest tightness, shortness of breath, trouble breathing or wheezing.
    Medical Conditions Aggravated by Exposure: Hypersensitivity to material; respiratory depression; existing
    cardiac conditions; broken or inflammed skin, burns, or open wounds at the place of application. More can be
    absorbed into the body quickly, which increases the chance of side effects; Liver disease (severe). The risk
    of side effects may be increased because of the slower removal of lidocaine from the body.

Section 12. Ecological Information
    Ecotoxicity        Not available.    
    BOD5 and COD        Not available.    
    Possibly hazardous short term degradation products are not likely. However, long term degradation products
    Products of Biodegradation
    may arise.
    Toxicity of the Products        The products of degradation are more toxic.    
    of Biodegradation
    Not available.
    Special Remarks on the
    Products of Biodegradation

Section 13. Disposal Considerations
    Waste must be disposed of in accordance with federal, state and local environmental
    Waste Disposal
    control regulations.
    Lidocaine Hydrochloride monohydrate

Section 14. Transport Information
    DOT Classification        Not a DOT controlled material (United States).    
    Not applicable.
    Not applicable.
    Special Provisions for
    DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
    No products were found. It is not listed on the TSCA inventory because it is a hydrate.
    Federal and State
    California prop. 65: This product contains the following ingredients for which the State of California has
    found to cause cancer which would require a warning under the statute: No products were found.
    Proposition 65
    California prop. 65: This product contains the following ingredients for which the State of California has
    found to cause birth defects which would require a warning under the statute: No products were found.
    Other Regulations        OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).    
    EINECS: This product is not on the European Inventory of Existing Commercial Chemical Substances.
    Canada: Not listed on Canadian Domestic Substance List (DSL) or Canadian Non- Domestic Substance List
    China: Not listed on National Inventory.
    Japan: Not listed on National Inventory (ENCS).
    Korea: Not listed on National Inventory (KECI).
    Philippines: Not listed on National Inventory (PICCS).
    Australia: Not listed on AICS.
    WHMIS (Canada) Not available under WHMIS (Canada).
    Other Classifications
    DSCL (EEC)        R22- Harmful if swallowed.        S36- Wear suitable protective clothing.    
    S46- If swallowed, seek medical advice
    immediately and show this container or label.
    Health Hazard
    HMIS (U.S.A.)        2 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    2 0 Reactivity
    Specific hazard
    Personal Protection
    WHMIS (Canada)
    DSCL (Europe)
    TDG (Canada)
    Lidocaine Hydrochloride monohydrate
    ADR (Europe)
    Protective Equipment
    Lab coat.
    Dust respirator. Be sure to use an
    approved/certified respirator or


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