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2,4-Tolylene diisocyanate 584-84-9 MSDS
Name: Tolylene-2 4-diisocyanate Material Safety Data Sheet
Synonym: 4-Methyl-1,3-phenylene diisocyanate; TDI; Toluene-2,4-diisocyanate
CAS: 584-84-9
Section 1 - Chemical Product   MSDS Name:Tolylene-2 4-diisocyanate Material Safety Data Sheet
Synonym:4-Methyl-1,3-phenylene diisocyanate; TDI; Toluene-2,4-diisocyanate

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
584-84-9 Tolylene-2,4-diisocyanate >80 209-544-5
Hazard Symbols: T+
Risk Phrases: 26 36/37/38 40 42/43 52/53

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Very toxic by inhalation. Irritating to eyes, respiratory system and skin. Limited evidence of a carcinogenic effect. May cause sensitization by inhalation and skin contact. Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Water-reactive.
Potential Health Effects
Eye:
Causes eye irritation. Lachrymator (substance which increases the flow of tears).
Skin:
Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Organic isocyanates can cause local irritation and allergic reactions.
Ingestion:
Causes gastrointestinal tract irritation.
Inhalation:
May be fatal if inhaled. Causes respiratory tract irritation. At high concentrations, isocyanates affect mucous membranes of the respiratory tract and may lead to fatal pulmonary edema. Exposure to low and often even unmeasurable isocyanate concentration results in sensitization. Impaired lung functions (decreased ventilatory capacity) has been associated with overexposure to isocyanate.
Chronic:
Chronic overexposure to isocyanates has been reported to cause lung damage, including decreased lung fuction, which may be permanent.

Section 4 - FIRST AID MEASURES
  Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Get medical aid if symptoms occur.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Absorption of this product into the body may cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood).
Moderate degrees of cyanosis need to be treated only by supportive measures: bed rest and oxygen inhalation.

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use dry chemical or carbon dioxide.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Provide ventilation. Do not expose spill to water. Do not get water inside containers. Approach spill from upwind.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Do not allow contact with water. Isocyanates react with water to form CO2 gas. This gas can cause sealed containers to expand and possibly rupture.
Storage:
Keep refrigerated. (Store below 4C/39F.) Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture. Sometimes packaged under dry nitrogen.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 584-84-9: United States OSHA: ; 0.02 ppm Ceiling; 0.14 mg/m3 Ceiling Belgium - TWA: 0.005 ppm VLE; 0.037 mg/m3 VLE Belgium - STEL: 0.02 ppm VLE; 0.14 mg/m3 VLE Germany: 0.005 ppm TWA; 0.035 mg/m3 TWA Malaysia: 0.005 ppm TWA; 0.036 mg/m3 TWA Netherlands: 0.02 ppm STEL; 0.15 mg/m3 STEL Netherlands: 0.005 ppm MAC; 0.04 mg/m3 MAC Russia: 0.05 mg/m3 TWA Spain: 0.005 ppm VLA-ED; 0.036 mg/m3 VLA-ED Spain: 0.02 ppm VLA-EC; 0.14 mg/m3 VLA-EC Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Liquid
Color: clear, colorless to pale yellow
Odor: pungent odor - sharp odor
pH: Not available.
Vapor Pressure: 0.01 mm Hg @ 20 deg C
Viscosity: Not available.
Boiling Point: 115-120 deg C @ 10 mm Hg
Freezing/Melting Point: 12.5-13.5 deg C
Autoignition Temperature: > 620 deg C (> 1,148.00 deg F)
Flash Point: 127 deg C ( 260.60 deg F)
Explosion Limits, lower: 0.9 vol%
Explosion Limits, upper: 9.5 vol%
Decomposition Temperature:
Solubility in water: Reacts.
Specific Gravity/Density: 1.22 g/ml
Molecular Formula: C9H6N2O2
Molecular Weight: 174.16

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures. Hazardous polymerization and/or hazardous decomposition may occur on contact with water or on exposure to heat.
Conditions to Avoid:
Light, contact with water, heat.
Incompatibilities with Other Materials:
Water, oxidizing agents, bases, alcohols, amines, organic acids, organometallic compounds.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: May occur.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 584-84-9: CZ6300000 LD50/LC50:
CAS# 584-84-9: Draize test, rabbit, eye: 100 mg Severe; Draize test, rabbit, skin: 500 mg/24H Moderate; Inhalation, mouse: LC50 = 10 ppm/4H; Inhalation, rabbit: LC50 = 11 ppm/4H; Inhalation, rat: LC50 = 14 ppm/4H; Oral, rat: LD50 = 5800 mg/kg; Skin, rabbit: LD50 = >16 mL/kg.
Carcinogenicity:
Tolylene-2,4-diisocyanate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
  Other No information available.

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Shipping Name: TOLUENE DIISOCYANATE
Hazard Class: 6.1
UN Number: 2078
Packing Group: II
IMO
Shipping Name: TOLUENE DIISOCYANATE
Hazard Class: 6.1
UN Number: 2078
Packing Group: II
RID/ADR
Shipping Name: TOLUENE DIISOCYANATE
Hazard Class: 6.1
UN Number: 2078
Packing group: II
USA RQ: CAS# 584-84-9: 100 lb final RQ (Listed under Toluene diisocyanate); 45.4

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+
Risk Phrases:
R 26 Very toxic by inhalation.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
R 40 Limited evidence of a carcinogenic effect.
R 42/43 May cause sensitization by inhalation and
skin contact.
R 52/53 Harmful to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 23 Do not inhale gas/fumes/vapour/spray.
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 584-84-9: 2
Canada
CAS# 584-84-9 is listed on Canada's DSL List.
CAS# 584-84-9 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 584-84-9 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

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