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chloramphenicol palmitate 530-43-8 MSDS

Section 1. Chemical Product and Company Identification
    Chloramphenicol palmitate
    Common Name/
    Trade Name
    Chloramphenicol palmitate

Section 4. First Aid Measures
    Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least
    Eye Contact
    15 minutes. Cold water may be used. WARM water MUST be used. Get medical attention.
    In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove
    Skin Contact
    contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical
    Serious Skin Contact        Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention.    
    Inhalation        If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get    
    medical attention.
    Serious Inhalation        Not available.    
    Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
    unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Not available.
    Flash Points
    Not available.
    Flammable Limits
    These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds.
    Products of Combustion
    Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
    Non-flammable in presence of shocks.
    Various Substances
    Risks of explosion of the product in presence of mechanical impact: Not available.
    Explosion Hazards in
    Slightly explosive in presence of open flames and sparks.
    Presence of Various
    SMALL FIRE: Use DRY chemical powder.
    Fire Fighting Media
    LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
    and Instructions
    Material in powder form, capable of creating a dust explosion. As with most organic solids, fire is possible at elevated
    Special Remarks on
    Fire Hazards
    Fine dust dispered in air in sufficient concentrations, and in the presences of an ignition source is a potential dust
    Special Remarks on
    explosion hazard.
    Explosion Hazards

Section 6. Accidental Release Measures
    Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading
    Small Spill
    water on the contaminated surface and dispose of according to local and regional authority requirements.
    Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on
    Large Spill
    the contaminated surface and allow to evacuate through the sanitary system.
    Chloramphenicol palmitate

Section 7. Handling and Storage
    Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
    ingest. Do not breathe dust. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable
    respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid
    contact with skin and eyes.
    Keep container tightly closed. Keep container in a cool, well-ventilated area.

Section 8. Exposure Controls/Personal Protection
    Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
    Engineering Controls
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
    airborne contaminants below the exposure limit.
    Personal Protection        Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.    
    Personal Protection in Case Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to
    avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE
    of a Large Spill
    handling this product.
    Not available.
    Exposure Limits

Section 9. Physical and Chemical Properties
    Solid. (Powdered solid.)        Not available.    
    Physical state and        O dor    
    561.55 g/mole
    Molecular Weight
    Not available.
    pH (1% soln/water)
    Not available.
    Boiling Point
    87°C (188.6°F) - 95 C (203 F)
    Melting Point
    Not available.
    Critical Temperature
    Not available.
    Specific Gravity
    Not applicable.
    Vapor Pressure
    Not available.
    Vapor Density
    Not available.
    Not available.
    Odor Threshold
    Not available.
    Water/Oil Dist. Coeff.
    Not available.
    Ionicity (in Water)
    See solubility in water, methanol, diethyl ether.
    Dispersion Properties
    Easily soluble in methanol, diethyl ether.
    Very slightly soluble in cold water.
    Freely solubly in ethanol, chloroform, and benzene
    Chloramphenicol palmitate

Section 10. Stability and Reactivity Data
    The product is stable.
    Not available.
    Instability Temperature
    Conditions of Instability Excessive heat, dust generation.
    Incompatibility with various Not available.
    Not available.
    Not available.
    Special Remarks on
    Not available.
    Special Remarks on
    Will not occur.

Section 11. Toxicological Information
    Inhalation. Ingestion.
    Routes of Entry
    Acute oral toxicity (LD50): 2640 mg/kg [Mouse].
    Toxicity to Animals
    Chronic Effects on Humans May cause damage to the following organs: blood, bone marrow.
    Other Toxic Effects on        Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.    
    Not available.
    Special Remarks on
    Toxicity to Animals
    Human: passes through the placenta, excreted in maternal milk.
    Special Remarks on
    May cause adverse reproductive effects and birth defects (teratogenic).
    Chronic Effects on Humans
    May affect genetic material (mutagenic).
    May cause cancer.
    Acute Potential Health Effects:
    Special Remarks on other
    Skin: May cause skin irritation.
    Toxic Effects on Humans
    Eyes: May cause eye irritation.
    Inhalation: May cause upper respiratory tract and mucous membrane irritation.
    Ingestion: May be harmful if swallowed. May cause gastrointestinal tract irritation with hypermotility and diarrhea. It
    may affect the bone marrow and blood (anemia, clotting, eosinophilia). It may also affect behavior/nervous
    system(somnolence, ataxia, coma, convulsions,"pins and needles" or numbness in fingers ), metabolism, liver,
    cardiovascular system, respiration (cyanosis), and urinary system.
    Chronic Potential Health Effects:
    Ingestion: Repeated or prolonged ingestion will have similar effects to acute ingestion.

Section 12. Ecological Information
    Not available.
    Not available.
    BOD5 and COD
    Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may
    The products of degradation are more toxic than the product itself.
    Toxicity of the Products
    of Biodegradation
    Not available.
    Special Remarks on the
    Products of Biodegradation
    Chloramphenicol palmitate

Section 13. Disposal Considerations
    Waste must be disposed of in accordance with federal, state and local environmental control
    Waste Disposal

Section 14. Transport Information
    Not a DOT controlled material (United States).
    DO T Cl assi fi cati on
    Not applicable.
    Not applicable.
    Special Provisions for
    DO T (Pi ctograms)

Section 15. Other Regulatory Information and Pictograms
    No products were found.
    Federal and State
    California prop. 65: This product contains the following ingredients for which the State of California has found to
    cause cancer which would require a warning under the statute: No products were found.
    Proposition 65
    California prop. 65: This product contains the following ingredients for which the State of California has found to
    cause birth defects which would require a warning under the statute: No products were found.
    Other Regulations        OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).    
    EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS No.
    Canada: Not listed on Canadian Domestic Substance List (DSL) or Canadian Non-Domestic Substances List (NDSL)
    China: Not listed on National Inventory.
    Japan: Not isted on National Inventory (ENCS).
    Korea: Listed on National Inventory (KECI).
    Philippines: Listed on National Inventory (PICCS).
    Australia: Listed on AICS.
    WHMIS (Canada) Not controlled under WHMIS (Canada).
    Other Classifications
    DSCL (EEC)        Not available        Not applicable.    
    Health Hazard
    HMIS (U.S.A.)        1 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    1 0 Reactivity
    Specific hazard
    Personal Protection        E    
    WHMIS (Canada)
    DSCL (Europe)
    Chloramphenicol palmitate
    ADR (Europe)
    Protective Equipment
    Lab coat.
    Dust respirator. Be sure to use an
    approved/certified respirator or equivalent.


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