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methylprednisolone acetate
CAS No.: 53-36-1
Formula: C24H32O6
Exact Mass: 416.22000
Molecular Weight: 416.50700
PSA: 100.90000
LogP: 2.37440
Reference Price: $1,875/g Inquiry Now
methylprednisolone acetate 53-36-1 MSDS

Section 1. Chemical Product and Company Identification
    Methylprednisolone acetate        Catalog    
    Common Name/
    Trade Name
    CAS#        53-36-1    
    RTECS        TU4154050    
    TSCA        TSCA 8(b) inventory:    
    Methylprednisolone acetate
    Commercial Name(s)        Not available.    
    CI# Not available.
    Synonym        11,17,21-Trihydroxy-6-methyl-1,4-pregnadiene-3,20-dione acetate    
    Not available.
    Chemical Name
    Chemical Family        Not available.        CALL (310) 516-8000    
    Chemical Formula

Section 2.Composition and Information on Ingredients
    Exposure Limits
    TWA (mg/m3)        STEL (mg/m3) CEIL (mg/m3)    
    Name        CAS #        % by Weight    
    1) Methylprednisolone acetate        53-36-1        100    
    Toxicological Data        Methylprednisolone acetate    
    on Ingredients        LD50: Not available.    
    LC50: Not available.

Section 3. Hazards Identification
    Potential Acute Health Effects Hazardous in case of skin contact (irritant, permeator), of eye contact (irritant), of ingestion, of inhalation.
    Potential Chronic Health        Hazardous in case of skin contact (irritant, permeator), of eye contact (irritant), of ingestion, of inhalation.    
    Effects        CARCINOGENIC EFFECTS: Not available.    
    MUTAGENIC EFFECTS: Not available.
    TERATOGENIC EFFECTS: Not available.
    Methylprednisolone acetate

Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. Do not use an eye ointment. Seek medical attention.    
    Skin Contact        After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin    
    with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin.
    Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated
    clothing before reusing.
    Serious Skin Contact        Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical    
    Inhalation        Allow the victim to rest in a well ventilated area. Seek immediate medical attention.    
    Serious Inhalation        Not available.    
    Ingestion        Do not induce vomiting. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not    
    breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention.
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Flash Points        Not available.    
    Flammable Limits        Not available.    
    These products are carbon oxides (CO, CO2).
    Products of Combustion
    Fire Hazards in Presence of Not available.
    Various Substances
    Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
    of Various Substances        Risks of explosion of the product in presence of static discharge: Not available.    
    Fire Fighting Media        SMALL FIRE: Use DRY chemical powder.    
    and Instructions        LARGE FIRE: Use water spray, fog or foam. Do not use water jet.    
    Special Remarks on        Not available.    
    Fire Hazards
    Special Remarks on Explosion Not available.

Section 6. Accidental Release Measures
    Small Spill        Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by    
    spreading water on the contaminated surface and dispose of according to local and regional authority
    Large Spill
    Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water
    on the contaminated surface and allow to evacuate through the sanitary system.
    Methylprednisolone acetate

Section 7. Handling and Storage
    Precautions        Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the    
    residue under a fume hood. Ground all equipment containing material. Do not breathe dust. Wear suitable
    protective clothing In case of insufficient ventilation, wear suitable respiratory equipment If you feel unwell, seek
    medical attention and show the label when possible. Avoid contact with skin and eyes
    Storage        Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly    
    closed. Keep in a cool, well-ventilated place. Combustible materials should be stored away from extreme heat
    and away from strong oxidizing agents.

Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below    
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
    airborne contaminants below the exposure limit.
    Personal Protection        Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.    
    Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
    a Large Spill        to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist    
    BEFORE handling this product.
    Exposure Limits        Not available.    

Section 9. Physical and Chemical Properties
    Physical state and appearance Solid. (Crystalline solid.)        Odor        Not available.    
    Taste        Not available.    
    416.51 g/mole
    Molecular Weight
    Color        White.    
    pH (1% soln/water)        Not applicable.    
    Boiling Point        Decomposes.    
    Melting Point        206°C (402.8°F)    
    Critical Temperature        Not available.    
    Specific Gravity        Not available.    
    Not applicable.
    Vapor Pressure
    Vapor Density        Not available.    
    Volatility        Not available.    
    Odor Threshold        Not available.    
    Water/Oil Dist. Coeff.        Not available.    
    Not available.
    Ionicity (in Water)
    Dispersion Properties        Not available.    
    Very slightly soluble in methanol, acetone.
    Insoluble in cold water.

Section 10. Stability and Reactivity Data
    Stability        The product is stable.    
    Instability Temperature        Not available.    
    Conditions of Instability        Not available.    
    Incompatibility with various Not available.
    Methylprednisolone acetate
    Non-corrosive in presence of glass.
    Special Remarks on        Not available.    
    Special Remarks on        Not available.    

Section 11. Toxicological Information
    Routes of Entry        Dermal contact. Eye contact. Inhalation. Ingestion.    
    Toxicity to Animals        LD50: Not available.    
    LC50: Not available.
    Chronic Effects on Humans Not available.
    Other Toxic Effects on        Hazardous in case of skin contact (irritant, permeator), of ingestion, of inhalation.    
    Special Remarks on        Not available.    
    Toxicity to Animals
    Special Remarks on        Not available.    
    Chronic Effects on Humans
    Special Remarks on other        Not available.    
    Toxic Effects on Humans

Section 12. Ecological Information
    Not available.
    BOD5 and COD        Not available.    
    Products of Biodegradation        Possibly hazardous short term degradation products are not likely. However, long term degradation products may    
    Toxicity of the Products        The products of degradation are more toxic.    
    of Biodegradation
    Special Remarks on the        Not available.    
    Products of Biodegradation

Section 13. Disposal Considerations
    Waste Disposal

Section 14. Transport Information
    DOT Classification        Not a DOT controlled material (United States).    
    Identification        Not applicable.    
    Special Provisions for        Not applicable.    
    Methylprednisolone acetate
    DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
    TSCA 8(b) inventory: Methylprednisolone acetate
    Federal and State
    California        California prop. 65: This product contains the following ingredients for which the State of California has found    
    to cause cancer which would require a warning under the statute: No products were found.
    Proposition 65
    California prop. 65: This product contains the following ingredients for which the State of California has found
    to cause birth defects which would require a warning under the statute: No products were found.
    Other Regulations        Not available..    
    WHMIS (Canada) Not controlled under WHMIS (Canada).
    Other Classifications
    DSCL (EEC)        R36/38- Irritating to eyes and skin.    
    Health Hazard
    HMIS (U.S.A.)        2 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    2 0 Reactivity
    Specific hazard
    Personal Protection
    WHMIS (Canada)
    DSCL (Europe)
    TDG (Canada)
    ADR (Europe)
    Protective Equipment
    Lab coat.
    Dust respirator. Be sure to use an
    approved/certified respirator or
    Methylprednisolone acetate


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