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dimenhydrinate 523-87-5 MSDS

Section 1. Chemical Product and Company Identification
    Common Name/        DI127    
    Trade Name
    SPECTRUM CHEMICAL MFG. CORP.        RTECS        XH5082000    
    TSCA        TSCA 8(b) inventory:    
    Commercial Name(s)        Not available.    
    CI# Not available.
    Synonym        8-Chloro-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione compd.    
    with 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1);
    Diphenhydramine 8-chlorotheophylline;
    Ethylamine, N,N-dimethyl-2-(diphenylmethoxy)-,
    compd. with 8-chlorotheophylline;
    O-Benzhydryldimethylaminoethanol 8-chlorotheophyllinate;
    Benzhydryl-beta-dimethylaminoethylether 8-chlorotheophylline;
    compd. with 8-chlorotheophylline;
    8-Chlorotheophylline, compd.
    with 2-(diphenylmethoxy)-N,N-dimethylethylamine (1:1);
    Gravinol (antiemetic);
    Vomex A;
    Chemical Name        Theophylline, 8-chloro-, compd. with    
    2-(diphenylmethoxy)-N,N-dimethylethylamine (1:1)
    Not available.        CALL (310) 516-8000    
    Chemical Family
    Chemical Formula        C17H21NO.C7H7ClN4O2    

Section 2.Composition and Information on Ingredients
    Exposure Limits
    TWA (mg/m3) STEL (mg/m3) CEIL (mg/m3) % by Weight
    Name        CAS #    
    1) Dimenhydrinate        523-87-5        100    
    Toxicological Data        Not applicable.    
    on Ingredients

Section 3. Hazards Identification
    Potential Acute Health Effects Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation.
    CARCINOGENIC EFFECTS: Not available.
    Potential Chronic Health
    MUTAGENIC EFFECTS: Mutagenic for bacteria and/or yeast.
    TERATOGENIC EFFECTS: Not available.
    Repeated or prolonged exposure is not known to aggravate medical condition.

Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for    
    at least 15 minutes. Cold water may be used. Get medical attention if irritation occurs.
    Skin Contact
    Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation
    develops. Cold water may be used.
    Serious Skin Contact        Not available.    
    Inhalation        If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.    
    Get medical attention.
    Serious Inhalation        Not available.    
    Ingestion        Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an    
    unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen
    tight clothing such as a collar, tie, belt or waistband.
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Not available.
    Flash Points
    Flammable Limits        Not available.    
    Products of Combustion        These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds.    
    Fire Hazards in Presence of Slightly flammable to flammable in presence of open flames and sparks, of shocks, of heat.
    Various Substances
    Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
    Risks of explosion of the product in presence of static discharge: Not available.
    of Various Substances
    Fire Fighting Media        SMALL FIRE: Use DRY chemical powder.    
    LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
    and Instructions
    Special Remarks on        Material in powder form, capable of creating a dust explosion.    
    Fire Hazards
    Special Remarks on Explosion Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential
    dust explosion hazard.

Section 6. Accidental Release Measures
    Small Spill        Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by    
    spreading water on the contaminated surface and dispose of according to local and regional authority
    Large Spill        Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading    
    water on the contaminated surface and allow to evacuate through the sanitary system.

Section 7. Handling and Storage
    Precautions        Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not    
    ingest. Do not breathe dust. Wear suitable protective clothing. If ingested, seek medical advice immediately
    and show the container or the label. Keep away from incompatibles such as oxidizing agents.
    Keep container tightly closed. Keep container in a cool, well-ventilated area.

Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below    
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep
    exposure to airborne contaminants below the exposure limit.
    Personal Protection        Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.    
    Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be
    a Large Spill        used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a    
    specialist BEFORE handling this product.
    Exposure Limits        Not available.    

Section 9. Physical and Chemical Properties
    Physical state and appearance Solid. (Crystalline powder.)        Odor        Odorless.    
    Taste        Not available.    
    Molecular Weight        469.96 g/mole    
    Color        White.    
    pH (1% soln/water)        Not available.    
    Not available.
    Boiling Point
    Melting Point        102-107°C (215.6-224.6°F)    
    Not available.
    Critical Temperature
    Specific Gravity        Not available.    
    Vapor Pressure        Not applicable.    
    Vapor Density        Not available.    
    Volatility        Not available.    
    Not available.
    Odor Threshold
    Water/Oil Dist. Coeff.        Not available.    
    Not available.
    Ionicity (in Water)
    Dispersion Properties        Not available.    
    Solubility        Soluble in cold water.    
    Freely soluble in alcohol.
    Soluble in chloroform , benzene.
    Insoluble in diethyl ether.

Section 10. Stability and Reactivity Data
    Stability        The product is stable.    
    Not available.
    Instability Temperature
    Conditions of Instability        Excess heat, dust generation, incompatible materials    
    Incompatibility with various        Reactive with oxidizing agents.    
    Corrosivity        Non-corrosive in presence of glass.    
    Not available.
    Special Remarks on
    Special Remarks on        Not available.    
    Polymerization        Will not occur.    

Section 11. Toxicological Information
    Routes of Entry        Inhalation. Ingestion.    
    Toxicity to Animals        Acute oral toxicity (LD50): 1320 mg/kg [Rat].    
    Chronic Effects on Humans MUTAGENIC EFFECTS: Mutagenic for bacteria and/or yeast.
    Other Toxic Effects on        Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.    
    Special Remarks on        Not available.    
    Toxicity to Animals
    Special Remarks on        May affect genetic material (mutagenic)    
    Chronic Effects on Humans
    Special Remarks on other        Acute Potential Health Effects:    
    Toxic Effects on Humans        Skin: May cause skin irritation.    
    Eyes: May cause eye irritation.
    Inhalation: May cause respiratory tract irritation.
    Ingestion: May be harmul is swallowed. May cause dry mouth, adbominal distress vomiting, nausea,
    diarrhea or constipaton, anorexia. May affect behavior (central nervous system (drowsiness, lethargy, fatigue.
    excitement, hallucinations; hypnosis, convulsions, coma), cardiovascular system (cardiac arrhythmias).

Section 12. Ecological Information
    Ecotoxicity        Not available.    
    BOD5 and COD        Not available.    
    Products of Biodegradation        Possibly hazardous short term degradation products are not likely. However, long term degradation products    
    may arise.
    Toxicity of the Products        The products of degradation are as toxic as the product itself.    
    of Biodegradation
    Special Remarks on the        Not available.    
    Products of Biodegradation

Section 13. Disposal Considerations
    Waste Disposal        Waste must be disposed of in accordance with federal, state and local environmental    
    control regulations.

Section 14. Transport Information
    DOT Classification
    Not a DOT controlled material (United States).
    Not applicable.
    Not applicable.
    Special Provisions for
    DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
    California prop. 65: This product contains the following ingredients for which the State of California has found
    Federal and State
    to cause birth defects which would require a warning under the statute: No products were found.
    TSCA 8(b) inventory: Dimenhydrinate
    California        California prop. 65: This product contains the following ingredients for which the State of California has    
    Proposition 65        found to cause cancer which would require a warning under the statute: No products were found.    
    California prop. 65: This product contains the following ingredients for which the State of California has
    found to cause birth defects which would require a warning under the statute: No products were found.
    Other Regulations        EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS    
    No. 208-350-8).
    Canada: Listed on Canadian Domestic Substance List (DSL).
    China: Not listed on National Inventory.
    Japan: Not listed on National Inventory (ENCS).
    Korea: Listed on National Inventory (KECI).
    Philippines: Listed on National Inventory (PICCS).
    Australia: Listed on AICS.
    WHMIS (Canada) Not controlled under WHMIS (Canada).
    Other Classifications
    DSCL (EEC)        R22- Harmful if swallowed.        S46- If swallowed, seek medical advice    
    immediately and show this container or label.
    Health Hazard
    HMIS (U.S.A.)        1 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    1 0 Reactivity
    Specific hazard
    Personal Protection
    WHMIS (Canada)
    DSCL (Europe)
    TDG (Canada)
    ADR (Europe)
    Protective Equipment
    Lab coat.
    Dust respirator. Be sure to use an
    approved/certified respirator or


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