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cyproheptadine hydrochloride sesquihydrate 41354-29-4 MSDS

Section 1. Chemical Product and Company Identification
    Cyproheptadine Hydrochloride
    Common Name/
    Trade Name
    Commercial Name(s)
    Chemical Name
    Chemical Family
    Cyproheptadine Hydrochloride

Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at    
    least 15 minutes. Cold water may be used. Get medical attention.
    Skin Contact        In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove    
    contaminated clothing and shoes. Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes
    before reuse. Get medical attention.
    Serious Skin Contact        Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate    
    medical attention.
    Inhalation        If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get    
    medical attention.
    Serious Inhalation        Not available.    
    Ingestion        Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an    
    unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
    clothing such as a collar, tie, belt or waistband.
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Flash Points        CLOSED CUP: Higher than 93.3°C (200°F).    
    Flammable Limits        Not available.    
    Products of Combustion        These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds.    
    Fire Hazards in Presence of Slightly flammable to flammable in presence of open flames and sparks, of heat.
    Various Substances        Non-flammable in presence of shocks.    
    Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
    of Various Substances        Risks of explosion of the product in presence of static discharge: Not available.    
    Fire Fighting Media        SMALL FIRE: Use DRY chemical powder.    
    and Instructions        LARGE FIRE: Use water spray, fog or foam. Do not use water jet.    
    Special Remarks on        Not available.    
    Fire Hazards
    Special Remarks on Explosion Not available.

Section 6. Accidental Release Measures
    Small Spill        Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by    
    spreading water on the contaminated surface and dispose of according to local and regional authority
    Large Spill        Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water    
    on the contaminated surface and allow to evacuate through the sanitary system.
    Cyproheptadine Hydrochloride

Section 7. Handling and Storage
    Precautions        Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the    
    residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust.
    Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If
    ingested, seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes.
    Storage        Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 24°C (75.2°F).    

Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below    
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
    airborne contaminants below the exposure limit.
    Personal Protection        Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.    
    Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
    a Large Spill        to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist    
    BEFORE handling this product.
    Exposure Limits        Not available.    

Section 9. Physical and Chemical Properties
    Physical state and appearance Solid. (Solidcrystalline powder.)        Odor        Not available.    
    Not available.
    Molecular Weight        350.88 g/mole    
    White to yellowish.
    Not available.
    pH (1% soln/water)
    Boiling Point        Not available.    
    Melting Point        Not available.    
    Critical Temperature        Not available.    
    Specific Gravity        Not available.    
    Not applicable.
    Vapor Pressure
    Vapor Density        Not available.    
    Not available.
    Odor Threshold        Not available.    
    Water/Oil Dist. Coeff.        Not available.    
    Ionicity (in Water)        Not available.    
    Dispersion Properties        See solubility in water, methanol.    
    Solubility        Soluble in methanol.    
    Partially soluble in cold water.
    Very slightly soluble in diethyl ether.
    Sparingly soluble in ethanol.
    Cyproheptadine Hydrochloride

Section 10. Stability and Reactivity Data
    The product is stable.
    Instability Temperature        Not available.    
    Excess heat, incompatible materials.
    Conditions of Instability
    Not available.
    Incompatibility with various
    Corrosivity        Not available.    
    Special Remarks on        No information found.    
    Special Remarks on        Not available.    
    Polymerization        Will not occur.    

Section 11. Toxicological Information
    Routes of Entry        Inhalation. Ingestion.    
    Toxicity to Animals        Acute oral toxicity (LD50): 69 mg/kg [Mouse].    
    Chronic Effects on Humans May cause damage to the following organs: blood, the nervous system.
    Other Toxic Effects on        Hazardous in case of skin contact (irritant), of ingestion, of inhalation.    
    Special Remarks on        Lowest Published Toxic Dose (TDL) [Woman] - Route: Oral; Dose: 7 mg/kg    
    Toxicity to Animals
    Special Remarks on        May cause adverse reproductive effects (female fertility) and birth defects (teratogenic - fetal developmental    
    Chronic Effects on Humans
    abnormalities) based on animal data.
    May affect genetic material (mutagenic)
    Special Remarks on other        Acute Potential Health Effects:    
    Toxic Effects on Humans        Skin: May cause skin irritation.    
    Eyes: Dust may cause eye irritation.
    Inhalation: Dust may cause respiratory tract and mucous membrane irritation.
    Ingestion: Harmful if Swallowed. May cause gastrointestinal tract irriation/disturbances including nausea and
    vomiting. May affect the liver. May have addictive effects with alcohol and other CNS depressants such as
    hypnotics, sedataives, tranquilizers, and anti-anxiety agents.
    The toxicological properties of this substance have not fully investigated.

Section 12. Ecological Information
    Not available.
    BOD5 and COD        Not available.    
    Products of Biodegradation        Possibly hazardous short term degradation products are not likely. However, long term degradation products may    
    Toxicity of the Products        The products of degradation are as toxic as the product itself.    
    of Biodegradation
    Special Remarks on the        Not available.    
    Products of Biodegradation
    Cyproheptadine Hydrochloride

Section 13. Disposal Considerations
    Waste Disposal        Waste must be disposed of in accordance with federal, state and local environmental    
    control regulations.

Section 14. Transport Information
    DOT Classification        Not a DOT controlled material (United States).    
    Not applicable.
    Not applicable.
    Special Provisions for
    DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
    No products were found.
    Federal and State
    Proposition 65
    Other Regulations        OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).    
    EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.
    WHMIS (Canada) Not controlled under WHMIS (Canada).
    Other Classifications
    DSCL (EEC)        R22- Harmful if swallowed.        S2- Keep out of the reach of children.    
    R36/38- Irritating to eyes and skin.        S46- If swallowed, seek medical advice    
    immediately and show this container or label.
    Health Hazard
    HMIS (U.S.A.)        2 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    2 0 Reactivity
    Specific hazard
    Personal Protection
    WHMIS (Canada)
    DSCL (Europe)
    TDG (Canada)
    Cyproheptadine Hydrochloride
    ADR (Europe)
    Protective Equipment
    Lab coat.
    Dust respirator. Be sure to use an
    approved/certified respirator or


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