isophorone diisocyanate 4098-71-9 MSDS

Section I.Chemical Product and Company Identification
    Chemical Name        Isophorone Diisocyanate    
    (mixture of isomers)
    Portland OR
    Synonym        Cyclohexane,    
    5-Isocyanato-1-(Isocyanatomethyl)-1,3,3-Trimethyl- (9 CI)
    Chemical Formula        C12H18N2O2    
    CAS Number        4098-71-9    

Section II.        Composition and Information on Ingredients    
    CAS Number Percent (%)        TLV/PEL        Toxicology Data    
    Chemical Name
    Isophorone Diisocyanate        4098-71-9        Min. 99.0        ACGIH TLV-TWA: 0.005ppm        Rat LC50 (inhalation) 123mg/m3/4H    
    (mixture of isomers)        OSHA PEL TWA: 0.005ppm        Rat LD50 (oral) 4825mg/kg    
    (GC)
    (vacated)        Guinea Pig LD50 (inhalation)    
    OSHA STEL: 0.02ppm        118mg/m3/1H    

Section III. Hazards Identification
    Acute Health Effects        Highly toxic if ingested or inhaled. Avoid prolonged contact with this material. Overexposure may result in serious illness    
    or death.
    Corrosive to skin, eyes, and respiratory system. Liquid or spray mist may produce tissue damage, particularly in mucous
    membranes of the eyes, mouth and respiratory tract. Skin contact may produce burns. Eye contact can result in corneal
    damage or blindness. Inhalation of the spray mist may produce severe irritation of respiratory tract, characterized by
    coughing, choking, or shortness of breath. Corrosive materials may cause serious injury if ingested.
    Skin contact may result in sensitization. Always cover all exposed skin with an impermeable layer and use proper eye
    protection. A OSHA/MSHA approved dust and vapor respirator is required when working with this material.
    Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.
    CARCINOGENIC EFFECTS : Not available.
    Chronic Health Effects
    MUTAGENIC EFFECTS : Not available.
    TERATOGENIC EFFECTS : Not available.
    DEVELOPMENTAL TOXICITY: REPRODUCTIVE EFFECTS:
    Mouse TDLo (oral) 415mg/kg, female, 8-12Days of pregnancy.
    TOXIC EFFECTS:
    Effects on Newborn- Viability index.
    Repeated or prolonged contact with spray mist may produce chronic eye irritation and severe skin irritation. Repeated or
    prolonged exposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchial
    infection.

Section IV.        First Aid Measures    
    Eye Contact        Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15    
    minutes. Get medical attention.
    Skin Contact        In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing    
    before reuse. Thoroughly clean shoes before reuse. Get medical attention.
    Inhalation        If the victim is not breathing, perform mouth-to-mouth resuscitation. Loosen tight clothing such as a collar, tie, belt or    
    waistband. If breathing is difficult, oxygen can be administered. Seek medical attention if respiration problems do not
    improve.
    DO NOT INDUCE VOMITING. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing,
    Ingestion
    perform mouth-to-mouth resuscitation. Examine the lips and mouth to ascertain whether the tissues are damaged, a
    possible indication that the toxic material was ingested; the absence of such signs, however, is not conclusive.
    Continued on Next Page
    Isophorone Diisocyanate
    (mixture of isomers)

Section V.        Fire and Explosion Data    
    Auto-Ignition        Not available.    
    Flammability        May be combustible at high temperature.    
    Flash Points        Flammable Limits        Not available.    
    163°C (325.4°F).
    Combustion Products        These products are toxic carbon oxides (CO, CO2), nitrogen oxides (NO, NO2).    
    WARNING: Very toxic cyanide gas may be produced in a fire. Do not inhale.
    Fire Hazards
    Not available.
    Explosion Hazards        Risks of explosion of the product in presence of mechanical impact: Not available.    
    Risks of explosion of the product in presence of static discharge: Not available.
    Fire Fighting Media
    SMALL FIRE: Use DRY chemical powder.
    and Instructions        LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet.    
    Consult with local fire authorities before attempting large scale fire-fighting operations.

Section VI.        Accidental Release Measures    
    Spill Cleanup        Highly toxic material. Corrosive material. Environmental hazard. Possible sensitizing material. Lachrymatory material.    
    Moisture sensitive material.
    Instructions
    Stop leak if without risk. Absorb with DRY earth, sand or other non-combustible material. DO NOT get water inside
    container. DO NOT touch spilled material. Use water spray curtain to divert vapor drift. Prevent entry into sewers,
    basements or confined areas; dike if needed. Eliminate all sources of ignition. Consult federal, state, and/or local
    authorities for assistance on disposal. Be careful that the product is not present at a concentration level above TLV.
    Check TLV on the MSDS and with local authorities.

Section VII. Handling and Storage
    HIGHLY TOXIC. CORROSIVE. ENVIRONMENTAL HAZARD. POSSIBLE SENSITIZER. LACHRYMATOR. MOISTURE
    Handling and Storage
    SENSITIVE. Keep container dry. Keep away from heat. Mechanical exhaust required. When not in use, tightly seal the
    Information
    container and store in a dry, cool place. Avoid excessive heat and light. DO NOT ingest. Do not breathe gas/fumes/
    vapor/spray. Never add water to this product. Wear suitable protective clothing. If ingested, seek medical advice
    immediately and show the container or the label. Treat symptomatically and supportively.
    Always store away from incompatible compounds such as oxidizing agents, acids.

Section VIII. Exposure Controls/Personal Protection
    Engineering Controls        Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their    
    respective threshold limit value. Ensure that eyewash station and safety shower is proximal to the work-station location.
    Personal Protection        Face shield. Lab coat. Vapor respirator. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a    
    specialist BEFORE handling this product. Be sure to use a MSHA/NIOSH approved respirator or equivalent.
    Exposure Limits        ACGIH TLV-TWA: 0.005ppm    
    OSHA PEL TWA: 0.005ppm (vacated)
    OSHA STEL: 0.02ppm

Section IX. Physical and Chemical Properties
    Liquid. (Colorless to slightly yellow.)        Solubility    
    Physical state @ 20°C        Completely miscible with esters, ketones,    
    ethers, and aromatic and aliphatic
    1.056 (water=1)        hydrocarbons.    
    Specific Gravity
    Molecular Weight        222.29        Partition Coefficient        Not available.    
    Boiling Point
    158 to 159°C (316.4 to 318.2°F)        Vapor Pressure        0 kPa (@ 20°C)    
    Melting Point        -60°C (-76°F)        Vapor Density        Not available.    
    Refractive Index        Not available.        Volatility        Not available.    
    Critical Temperature        Not available.        Odor        Not available.    
    Viscosity        Not available.        Taste        Not available.    

Section X.        Stability and Reactivity Data    
    Stability    
This material is stable if stored under proper conditions. (See Section VII for instructions)    
    Conditions of Instability        Protect from moisture. Avoid excessive heat and light.    
    Incompatibilities        Reactive with strong oxidizing agents, strong acids, alcohols, water, phenols, amines, mercaptans, amides, urethanes,    
    and ureas.
    Continued on Next Page
    Isophorone Diisocyanate
    (mixture of isomers)

Section XI.        Toxicological Information    
    RTECS Number        NQ9370000    
    Routes of Exposure        Eye Contact. Ingestion. Inhalation. Skin contact.    
    Rat LC50 (inhalation) 123mg/m3/4H
    Toxicity Data
    Rat LD50 (oral) 4825mg/kg
    Guinea Pig LD50 (inhalation) 118mg/m3/1H
    CARCINOGENIC EFFECTS : Not available.
    Chronic Toxic Effects
    MUTAGENIC EFFECTS : Not available.
    TERATOGENIC EFFECTS : Not available.
    DEVELOPMENTAL TOXICITY: REPRODUCTIVE EFFECTS:
    Mouse TDLo (oral) 415mg/kg, female, 8-12Days of pregnancy.
    TOXIC EFFECTS:
    Effects on Newborn- Viability index.
    Repeated or prolonged contact with spray mist may produce chronic eye irritation and severe skin irritation. Repeated or
    prolonged exposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchial infection.
    Highly toxic if ingested or inhaled. Avoid prolonged contact with this material. Overexposure may result in serious illness
    Acute Toxic Effects
    or death.
    Corrosive to skin, eyes, and respiratory system. Liquid or spray mist may produce tissue damage, particularly in mucous
    membranes of the eyes, mouth and respiratory tract. Skin contact may produce burns. Eye contact can result in corneal
    damage or blindness. Inhalation of the spray mist may produce severe irritation of respiratory tract, characterized by
    coughing, choking, or shortness of breath. Corrosive materials may cause serious injury if ingested.
    Skin contact may result in sensitization. Always cover all exposed skin with an impermeable layer and use proper eye
    protection. A OSHA/MSHA approved dust and vapor respirator is required when working with this material.
    Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.

Section XII.        Ecological Information    
    Ecotoxicity        This material is toxic to aquatic organisms and may cause long term adverse effects to the aquatic environment.    
    Environmental Fate        Not available.    

Section XIII. Disposal Considerations
    Waste Disposal        Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a    
    combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all
    federal, state and local regulations when disposing of the substance.

Section XIV. Transport Information
    DOT Classification        CLASS 6.1: Toxic material.    
    PIN Number
    Proper Shipping Name        Isophorone diisocyanate    
    Packing Group (PG)        III    
    DOT Pictograms

Section XV. Other Regulatory Information and Pictograms
    TSCA Chemical Inventory        This compound is ON the EPA Toxic Substances Control Act (TSCA) inventory list.    

This product is subject to SARA Section 313 reporting requirements.
    (EPA)
    WHMIS Classification        CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).    
    CLASS E: Corrosive liquid.
    (Canada)
    On DSL.
    EINECS Number (EEC)        223-861-6    
    EEC Risk Statements        R23/24/25- Toxic by inhalation, in contact with skin and if swallowed.    
    R34- Causes burns.
    R42/43- May cause sensitization by inhalation and skin contact.
    R50- Very toxic to aquatic organisms.
    R53- May cause long-term adverse effects in the aquatic environment.
    Japanese Regulatory Data
    ENCS No. 3-2492
    Continued on Next Page


SECTION 16 - ADDITIONAL INFORMATION
N/A

Home   |   Announcement   |   Partners   |   Business Cooperation   |   Suppliers   |   Products    |   About Us   |   Contact Us   |   Privacy Policy   |   Terms & Conditions   |   Legal Statement

Copyright © 2013-2016 MOLBASE All Rights Reserved ICP Shanghai 14014220