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clemastine fumarate 14976-57-9 MSDS

Section 1. Chemical Product and Company Identification
    Clemastine Fumarate
    Common Name/
    Trade Name
    Clemastine Fumarate

Section 4. First Aid Measures
    Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least
    Eye Contact
    15 minutes. Cold water may be used. WARM water MUST be used. Get medical attention.
    In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove
    Skin Contact
    contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical
    Serious Skin Contact        Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention.    
    Inhalation        If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get    
    medical attention.
    Serious Inhalation        Not available.    
    Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
    unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Not available.
    Flash Points
    Not available.
    Flammable Limits
    These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds.
    Products of Combustion
    Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
    Non-flammable in presence of shocks.
    Various Substances
    Risks of explosion of the product in presence of mechanical impact: Not available.
    Explosion Hazards in
    Risks of explosion of the product in presence of static discharge: Not available.
    Presence of Various
    SMALL FIRE: Use DRY chemical powder.
    Fire Fighting Media
    LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
    and Instructions
    Not available.
    Special Remarks on
    Fire Hazards
    Not available.
    Special Remarks on
    Explosion Hazards

Section 6. Accidental Release Measures
    Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading
    Small Spill
    water on the contaminated surface and dispose of according to local and regional authority requirements.
    Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on
    Large Spill
    the contaminated surface and allow to evacuate through the sanitary system.
    Clemastine Fumarate

Section 7. Handling and Storage
    Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue
    under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. Wear suitable
    protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical
    advice immediately and show the container or the label. Avoid contact with skin and eyes.
    Light Sensitive. Heat Sensitive. Store in light resistant containers. Keep container tightly closed. Keep container in
    a cool, well-ventilated area. Do not store above 25°C (77°F).

Section 8. Exposure Controls/Personal Protection
    Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
    Engineering Controls
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
    airborne contaminants below the exposure limit.
    Personal Protection        Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.    
    Personal Protection in Case Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to
    avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE
    of a Large Spill
    handling this product.
    Not available.
    Exposure Limits

Section 9. Physical and Chemical Properties
    Solid.        Odorless.    
    Physical state and        O dor    
    Not available.
    459.97 g/mole
    Molecular Weight
    Colorless to light yellow.
    Not available.
    pH (1% soln/water)
    Not available.
    Boiling Point
    178°C (352.4°F)
    Melting Point
    Not available.
    Critical Temperature
    Not available.
    Specific Gravity
    Not applicable.
    Vapor Pressure
    Not available.
    Vapor Density
    Not available.
    Not available.
    Odor Threshold
    Not available.
    Water/Oil Dist. Coeff.
    Not available.
    Ionicity (in Water)
    Not available.
    Dispersion Properties
    Very slightly soluble in cold water.

Section 10. Stability and Reactivity Data
    The product is stable.
    Not available.
    Instability Temperature
    Conditions of Instability Excess heat, light
    Incompatibility with various Not available.
    Clemastine Fumarate
    Not available.
    Sensitive to light.
    Special Remarks on
    Heat sensitive.
    No more information found at this time
    Not available.
    Special Remarks on
    Will not occur.

Section 11. Toxicological Information
    Inhalation. Ingestion.
    Routes of Entry
    Toxicity to Animals        Acute oral toxicity (LD50): 730 mg/kg [Mouse].    
    Chronic Effects on Humans May cause damage to the following organs: central nervous system (CNS).
    Hazardous in case of skin contact (irritant), of ingestion, of inhalation.
    Other Toxic Effects on
    Not available.
    Special Remarks on
    Toxicity to Animals
    Not available.
    Special Remarks on
    Chronic Effects on Humans
    Aute Potential Health Effects:
    Special Remarks on other
    May cause skin irritation.
    Toxic Effects on Humans
    Eyes: May cause eye irritation.
    Inhalation: May cause respiratory tract irritation with tightness of chest and wheezing, nasal stuffiness, and thickening
    of bronchial secretions.
    Ingestion: May cause gastrointestinal tract irritation with nausea, vomiting, diarrhea, dry mouth, thirst. May affect
    behavior/central nervous system, and vision. Symptoms may include hallucinations, muscle contaction or spasticity,
    somnolence, excitement, change in motor activity, drowsiness, sedation, dizziness, impaired speech, incoordination,
    fixed dilated pupils, interference with color vision, blurred vision, fever, flushed face, hot dry skin. It may also affect
    cardiovascular system with tachycardia and hypotension.

Section 12. Ecological Information
    Not available.
    Not available.
    BOD5 and COD
    Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may
    The products of degradation are more toxic than the product itself.
    Toxicity of the Products
    of Biodegradation
    Not available.
    Special Remarks on the
    Products of Biodegradation

Section 13. Disposal Considerations
    Waste must be disposed of in accordance with federal, state and local environmental control
    Waste Disposal
    Clemastine Fumarate

Section 14. Transport Information
    DO T Cl assi fi cati on        Not a DOT controlled material (United States).    
    Not applicable.
    Not applicable.
    Special Provisions for
    DO T (Pi ctograms)

Section 15. Other Regulatory Information and Pictograms
    No products were found.
    Federal and State
    Proposition 65
    EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.
    Other Regulations
    WHMIS (Canada) Not controlled under WHMIS (Canada).
    Other Classifications
    R36/38- Irritating to eyes and skin.        S2- Keep out of the reach of children.    
    DSCL (EEC)
    S46- If swallowed, seek medical advice
    immediately and show this container or label.
    HMIS (U.S.A.)        Health Hazard        2 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    2 0 Reactivity
    Specific hazard
    Personal Protection
    WHMIS (Canada)
    DSCL (Europe)
    ADR (Europe)
    Protective Equipment
    Clemastine Fumarate
    Lab coat.
    Dust respirator. Be sure to use an
    approved/certified respirator or equivalent.


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