Henan Tianfu Chemical Co.,LtdPurity: 99%Lead Time: 2 Day
Shanghai Send Pharmaceutical T...Purity: 98%Lead Time: 7 Day
Hangzhou Hairui chemical co.,l...Purity: 98%Lead Time: 7 Day
xi an jia bo ying sheng wu ke ...Purity: 99%Lead Time: 7 Day
su zhou fu lu sheng wu ke ji y...Purity: 99%Lead Time: 1 Day
SAFETY DATA SHEET
Section 1. IDENTIFICATION
Product name: Lomustine
Revision number: 5
Section 2. HAZARDS IDENTIFICATION
PHYSICAL HAZARDS Not classified
Acute toxicity (Oral) Category 3
Germ cell mutagenicity
Carcinogenicity Category 1B
Specific target organ toxicity Liver, Bone marrow
- Single exposure [Category 1]
Specific target organ toxicity Organs
- Single exposure [Category 2]
Specific target organ toxicity Bone marrow
- Repeated exposure [Category 1]
Specific target organ toxicity Liver, Nervous system, Kidney, Lung
- Repeated exposure [Category 2]
ENVIRONMENTAL HAZARDS Not classified
GHS label elements, including precautionary statements
Pictograms or hazard symbols
Hazard statements Toxic if swallowed
May cause genetic defects
May cause cancer
May damage fertility or the unborn child
Causes damage to organs : Liver Bone marrow
May cause damage to organs : Organs
Causes damage to organs through prolonged or repeated
exposure : Bone marrow
May cause damage to organs through prolonged or
repeated exposure : Liver Nervous system Kidney Lung
Section 2. HAZARDS IDENTIFICATION
[Prevention] Obtain special instructions before use.
Do not handle until all safety precautions have been read and understood.
Do not breathe dust/fume/gas/mist/vapours/spray.
Do not eat, drink or smoke when using this product.
Wash hands thoroughly after handling.
Use personal protective equipment as required.
[Response] IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. Rinse
IF exposed or concerned: Get medical advice/attention.
[Storage] Store locked up.
[Disposal] Dispose of contents/container through a waste management company authorized by
the local government.
Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
CAS Number: 13010-47-4
Chemical Formula: C9H16ClN3O2
Section 4. FIRST AID MEASURES
Inhalation: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Get medical advice/attention.
Skin contact: Remove/Take off immediately all contaminated clothing. Gently wash with plenty of
soap and water. Get medical advice/attention.
Eye contact: Rinse cautiously with water for several minutes. Remove contact lenses, if present
and easy to do. Get medical advice/attention.
Ingestion: Immediately call a POISON CENTER or doctor/physician. Rinse mouth.
Protection of first-aiders: A rescuer should wear personal protective equipment, such as rubber gloves and air-
Section 5. FIRE-FIGHTING MEASURES
Suitable extinguishing Dry chemical, foam, water spray, carbon dioxide.
Specific hazards arising Explosion risk in case of fire. Fight fire remotely due to the risk of explosion.
from the chemical: Take care as it may decompose upon combustion or in high temperatures to
generate poisonous fume.
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Keep containers cool by
spraying with water. Eliminate all ignition sources if safe to do so.
Special protective When extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:
Section 6. ACCIDENTAL RELEASE MEASURES
Personal precautions, Use extra personal protective equipment (P3 filter respirator for toxic particles). Keep
protective equipment and people away from and upwind of spill/leak. Entry to non-involved personnel should
emergency procedures: be controlled around the leakage area by roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
up: appropriate laws and regulations.
Section 7. HANDLING AND STORAGE
Precautions for safe handling
Section 7. HANDLING AND STORAGE
Technical measures: Handling is performed in a well ventilated place. Wear suitable protective equipment.
Be careful not to cause leakage, overflow, or dispersion. Steam should not be
generated unnecessarily. Keep away from heat/sparks/open flame/hot surfaces. -No
smoking. Take measures to prevent the build up of electrostatic charge. Use
explosion-proof equipment. Avoid shock and friction. Wash hands and face before
breaks and immediately after handling the product.
Use a closed system if possible. Use a local exhaust if dust or aerosol will be
Advice on safe handling: Avoid all contact!
Conditions for safe storage, including any
Storage conditions: Keep container tightly closed. Store in a freezer.
Store locked up.
Be sure not to give the container unexpected impacts, such as falling down or falling
Store away from incompatible materials such as oxidizing agents.
Packaging material: Comply with laws.
Section 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering controls: Install a closed system or local exhaust. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Dust respirator, self-contained breathing apparatus(SCBA), supplied air respirator,
etc. Use respirators approved under appropriate government standards and follow
local and national regulations.
Hand protection: Impervious gloves.
Safety goggles. A face-shield, if the situation requires.
Skin and body protection: Impervious protective clothing. Protective boots, if the situation requires.
Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C): Solid
Colour: Slightly pale yellow - Yellow
No data available
pH: No data available
Melting point/freezing point:91°C
Boiling point/range: No data available
Flash point: No data available
Flammability or explosive
Lower: No data available
Upper: No data available
Relative density: No data available
[Water] No data available
[Other solvents] No data available
Log Pow: 2.83
Section 10. STABILITY AND REACTIVITY
Chemical stability: Stable under proper conditions.
Possibility of hazardous May explosively decompose on heating, shock, friction, etc.
Heat, Shock, Friction
Conditions to avoid:
Incompatible materials: Oxidizing agents, Strong bases
Hazardous decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx), Hydrogen chloride
Section 11. TOXICOLOGICAL INFORMATION
Acute Toxicity: orl-rat LD50:70 mg/kg
ipr-rat LD50:50350 ug/kg
scu-mus LD50:54 mg/kg
Skin corrosion/irritation: No data available
Serious eye No data available
Germ cell mutagenicity: mmo-sat 100 ug/plate (+S9)
mmo-sat 7 ug/plate (-S9)
cyt-hmn-lym 700 ug/L
dnd-mus-ivn 48 mg/kg
Carcinogenicity: orl-rat TDLo:50 mg/kg
skn-mus TDLo:276 mg/kg/23W-I
IARC = Group 2A (Probably carcinogenic to humans)
NTP = b (Reasonably anticipated to be carcinogens)
No data available
RTECS Number: YS4900000
Section 12. ECOLOGICAL INFORMATION
Fish: No data available
Crustacea: No data available
Algae: No data available
Persistence / degradability: No data available
Mobility in soil
Soil adsorption (Koc): 200
1.8 x 10-5
Section 13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities and an expert of disposal. You may be able
to dissolve or mix material with a combustible solvent and little by little burn in a chemical incinerator equipped with
an afterburner and scrubber system. If a large amount of the substance is burned at a time, an explosion may
occur. Observe all federal, state and local regulations when disposing of the substance.
Section 14. TRANSPORT INFORMATION
Hazards Class: 6.1: Toxic substance.
Proper shipping name: Toxic solid, organic, n.o.s.
Packing group: III
Section 15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
loading and unloading were prescribed.
SECTION 16 - ADDITIONAL INFORMATION