resorcinol 108-46-3 MSDS
Name: Resorcinol Material Safety Data Sheet
Synonym: 1,3-Benzenediol; m-Dihydroxybenzene; Resorcin; 1,3-Dihydroxybenzene; m-Benzenediol; m-Hydroxyphenol; 3-Hydroxyphenol
CAS: 108-46-3
Section 1 - Chemical Product   MSDS Name:Resorcinol Material Safety Data Sheet
Synonym:1,3-Benzenediol; m-Dihydroxybenzene; Resorcin; 1,3-Dihydroxybenzene; m-Benzenediol; m-Hydroxyphenol; 3-Hydroxyphenol

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
108-46-3 Resorcinol 100 203-585-2
Hazard Symbols: XN N
Risk Phrases: 22 36/38 50

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Harmful if swallowed. Irritating to eyes and skin. Very toxic to aquatic organisms.Dangerous for the environment.Hygroscopic (absorbs moisture from the air).
Potential Health Effects
Eye:
Contact with eyes may cause severe irritation, and possible eye burns. Contact of the eye with resorcinol has caused necrosis and corneal perforation.
Skin:
Causes moderate skin irritation. May be absorbed through the skin in harmful amounts. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. If absorbed, may cause symptoms similar to those for ingestion.
Resorcinol has been known to cause hyperemia (an excess of blood in a part), itch, dermatitis, edema, and corrosion.
Ingestion:
May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns. May cause methemoglobinemia, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), convulsions, and death.
Inhalation:
Dust is irritating to the respiratory tract. Causes irritation of the mucous membrane and upper respiratory tract.
Chronic:
May cause liver and kidney damage. Repeated exposure may cause sensitization dermatitis. Repeated exposure may cause damage to the spleen.

Section 4 - FIRST AID MEASURES
  Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid immediately.
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Persons with skin problems or liver, kidney, lung, or blood diseases may be at increased risk from exposure to this substance. Absorption of this product into the body may cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood).
Moderate degrees of cyanosis need to be treated only by supportive measures: bed rest and oxygen inhalation. If cyanosis is severe, intravenous injection of Methylene Blue, 1mg/kg of body weight may be of value.

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Dusts at sufficient concentrations can form explosive mixtures with air. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Water spray may cause frothing. Cool containers with flooding quantities of water until well after fire is out. In case of fire, use carbon dioxide, dry chemical powder or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Store protected from light.
Store protected from air. Use only with adequate ventilation. Avoid breathing dust.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Do not expose to air. Store protected from light.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Exposure Limits CAS# 108-46-3: United Kingdom, WEL - TWA: 10 ppm TWA; 46 mg/m3 TWA United Kingdom, WEL - STEL: 20 ppm STEL; 92 mg/m3 STEL Belgium - TWA: 10 ppm VLE; 46 mg/m3 VLE Belgium - STEL: 20 ppm VLE; 91 mg/m3 VLE France - VME: 10 ppm VME; 45 mg/m3 VME Germany: 10 ppm TWA; 45 mg/m3 TWA Malaysia: 10 ppm TWA; 45 mg/m3 TWA Netherlands: 10 ppm MAC; 45 mg/m3 MAC Spain: 10 ppm VLA-ED; 46 mg/m3 VLA-ED Spain: 20 ppm VLA-EC; 92 mg/m3 VLA-EC Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective clothing to prevent skin exposure.
Clothing:
Wear appropriate protective gloves to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Powder
Color: white
Odor: pleasant odor
pH: 5.2 in solution
Vapor Pressure: 1 mm Hg @ 108.4 deg C
Viscosity: Not available.
Boiling Point: 276 deg C
Freezing/Melting Point: 110.7 deg C
Autoignition Temperature: 608 deg C ( 1,126.40 deg F)
Flash Point: 127 deg C ( 260.60 deg F)
Explosion Limits, lower: 1.4% @ 200C
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Soluble.
Specific Gravity/Density: 1.272
Molecular Formula: C6H6O2
Molecular Weight: 110.11

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable at normal temperatures in tightly closed containers under an inert atmosphere. Substance undergoes color change upon exposure to light and air. May undergo auto-oxidation at 25C.
Conditions to Avoid:
Light, dust generation, exposure to air, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, bases, nitric acid, albumin, iron salts, antipyrine, acetanilide, menthol, urethane, spirit nitrous ether, camphor.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 108-46-3: VG9625000 LD50/LC50:
CAS# 108-46-3: Draize test, rabbit, eye: 100 mg Severe; Draize test, rabbit, skin: 500 mg; Draize test, rabbit, skin: 20 mg/24H Moderate; Oral, mouse: LD50 = 200 mg/kg; Oral, rat: LD50 = 301 mg/kg; Oral, rat: LD50 = 301 mg/kg; Skin, rabbit: LD50 = 3360 mg/kg; Skin, rabbit: LD50 = 3360 mg/kg.
Oral human LDLo: 29 mg/kg.
TDLo: 4800 mg/kg/12W intermittent - produced skin tumors.
Carcinogenicity:
Resorcinol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
  Ecotoxicity:
Fish: Fathead Minnow: LC50 = 88.6 mg/L; 24Hr; UnspecifiedFish: Fathead Minnow: LC50 = 72.6 mg/L; 48 Hr; UnspecifiedFish: Fathead Minnow: LC50 = 53.4 mg/L; 96 Hr; UnspecifiedIf released to soil or water, biodegradation is expected to be an important fate process based on the results of a number of biological screening studies which have suggested that resorcinol is readily biodegradable.
Resorcinol may react relatively rapidly in sunlit natural water with photochemically produced oxidants such as hydroxyl and peroxy radicals. Resorcinol is expected to leach readily in soil; however, leaching may not be important if concurrent biodegradation occurs at Other Dangerous to aquatic life in high concentrations.

Section 13 - DISPOSAL CONSIDERATIONS
  Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.

Section 14 - TRANSPORT INFORMATION
 
IATA
Shipping Name: RESORCINOL
Hazard Class: 6.1
UN Number: 2876
Packing Group: III
IMO
Shipping Name: RESORCINOL
Hazard Class: 6.1
UN Number: 2876
Packing Group: III
RID/ADR
Shipping Name: RESORCINOL
Hazard Class: 6.1
UN Number: 2876
Packing group: III
USA RQ: CAS# 108-46-3: 5000 lb final RQ; 2270 kg final RQ

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN N
Risk Phrases:
R 22 Harmful if swallowed.
R 36/38 Irritating to eyes and skin.
R 50 Very toxic to aquatic organisms.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 108-46-3: 1
Canada
CAS# 108-46-3 is listed on Canada's DSL List.
CAS# 108-46-3 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 108-46-3 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

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