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3-chlorophenol 108-43-0 MSDS

Section I.Chemical Product and Company Identification
    Chemical Name 3-Chlorophenol
    Portland OR
    Synonym        Not available.    
    Chemical Formula        ClC6H4OH    
    CAS Number        108-43-0    

Section II.        Composition and Information on Ingredients    
    Chemical Name        CAS Number Percent (%)        TLV/PEL        Toxicology Data    
    3-Chlorophenol        108-43-0        Min. 98.0        This chemical is classified as a        Rat LD50 (oral) 570mg/kg    
    possible carcinogen. There is        Rat LD50 (intraperitoneal)    
    (GC)
    no acceptable exposure limit        355mg/kg    
    for a carcinogen.        Mouse LD50 (oral) 521mg/kg    

Section III. Hazards Identification
    Acute Health Effects        Corrosive to skin, eyes, and respiratory system. Liquid or spray mist may produce tissue damage, particularly in mucous    
    membranes of the eyes, mouth and respiratory tract. Skin contact may produce burns. Eye contact can result in corneal
    damage or blindness. Inhalation of the spray mist may produce severe irritation of respiratory tract, characterized by
    coughing, choking, or shortness of breath. Corrosive materials may cause serious injury if ingested.
    Harmful if ingested or inhaled. Minimize exposure to this material. Severe overexposure can result in injury or death.
    Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.
    Chronic Health Effects        CARCINOGENIC EFFECTS : Not available.    
    MUTAGENIC EFFECTS : Not available.
    TERATOGENIC EFFECTS :Tumorigenic Effects:
    Mouse TDLo (dermal) 6000 mg/kg/15 weeks, intermittent.
    Toxic Effects:
    Tumorigenic - Equivocal tumorigenic agent by RTECS criteria.
    Skin and Appendages - Tumors.
    DEVELOPMENTAL TOXICITY: Not available.
    Repeated exposure of the eyes to a low level of dust can produce eye irritation. Repeated skin exposure can produce
    local skin destruction, or dermatitis. Repeated inhalation of dust can produce varying degree of respiratory irritation or
    lung damage.

Section IV.        First Aid Measures    
    Eye Contact        Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15    
    minutes. Get medical attention.
    Skin Contact        In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing    
    before reuse. Thoroughly clean shoes before reuse. Get medical attention.
    Inhalation        If the victim is not breathing, perform mouth-to-mouth resuscitation. Loosen tight clothing such as a collar, tie, belt or    
    waistband. If breathing is difficult, oxygen can be administered. Seek medical attention if respiration problems do not
    improve.
    Ingestion        DO NOT INDUCE VOMITING Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing,    
    perform mouth-to-mouth resuscitation. Examine the lips and mouth to ascertain whether the tissues are damaged, a
    possible indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. SEEK
    IMMEDIATE MEDICAL ATTENTION in case of ingestion of a radioactive material.

Section V.        Fire and Explosion Data    
    Not available.
    Flammability        May be combustible at high temperature.        Auto-Ignition    
    Flash Points        Flammable Limits        Not available.    
    >110°C (230°F).
    Combustion Products        These products include toxic carbon oxides (CO,CO 2), halogenated compounds.    
    WARNING: Highly toxic HCl gas is produced during combustion.
    Fire Hazards
    Not available.
    Continued on Next Page
    3-Chlorophenol
    Risks of explosion of the product in presence of mechanical impact: Not available.
    Explosion Hazards
    Risks of explosion of the product in presence of static discharge: Not available.
    Fire Fighting Media        SMALL FIRE: Use DRY chemical powder.    
    and Instructions        LARGE FIRE: Use DRY chemical powder, carbon dioxide (CO 2), or appropriate foam. DO NOT use water jet.    
    Consult with local fire authorities before attempting large scale fire-fighting operations.

Section VI.        Accidental Release Measures    
    Spill Cleanup        Corrosive material. Harmful material.    
    Stop leak if without risk. If the product is in its solid form: Use a shovel to put the material into a convenient waste
    Instructions
    disposal container. If the product is in its liquid form: DO NOT get water inside container. Absorb with an inert material
    and put the spilled material in an appropriate waste disposal. DO NOT touch spilled material. Use water spray to reduce
    vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all sources of ignition.
    Consult federal, state, and/or local authorities for assistance on disposal.

Section VII. Handling and Storage
    Handling and Storage        CORROSIVE. HARMFUL. Keep container dry. Keep away from heat. Mechanical exhaust required. When not in use,    
    tightly seal the container and store in a dry, cool place. Avoid excessive heat and light. DO NOT ingest. Do not breathe
    Information
    dust. Never add water to this product. Wear suitable protective clothing. If ingested, seek medical advice immediately
    and show the container or the label. Treat symptomatically and supportively.
    Always store away from incompatible compounds such as oxidizing agents.

Section VIII. Exposure Controls/Personal Protection
    Engineering Controls        Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below    
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
    airborne contaminants below the exposure limit.
    Personal Protection        Face shield. Lab coat. Dust respirator. Boots. Gloves. A MSHA/NIOSH approved respirator must be used to avoid    
    inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling
    this product.
    Exposure Limits        This chemical is classified as a possible carcinogen. There is no acceptable exposure limit for a carcinogen.    

Section IX. Physical and Chemical Properties
    Physical state @ 20°C        Solid. (Yellow. )        Solubility    
    Slightly soluble in cold water.
    Soluble in alcohol, ether, caustic alkali
    1.218 (water=1)
    Specific Gravity        solutions.    
    Molecular Weight        128.56        Partition Coefficient    
    Not available.
    Boiling Point        Vapor Pressure    
    214°C (417.2°F) @ 760 mm Hg        0.125mm Hg @ 25°C    
    Melting Point        33 to 35°C (91.4 to 95°F)        Vapor Density        Not available.    
    Refractive Index        1.5565 @ 40°C        Volatility        Not available.    
    Critical Temperature        Not available.        Odor        Not available.    
    Viscosity        Not available.        Taste        Not available.    

Section X.        Stability and Reactivity Data    
    Stability    
This material is stable if stored under proper conditions. (See Section VII for instructions)    
    Conditions of Instability
    Avoid excessive heat and light.
    Incompatibilities
    Reactive with oxidizing agents, acid chlorides, and acid anhydrides.

Section XI. Toxicological Information
    RTECS Number        SK2450000    
    Routes of Exposure        Eye Contact. Ingestion. inhalation.    
    Toxicity Data        Rat LD50 (oral) 570mg/kg    
    Rat LD50 (intraperitoneal) 355mg/kg
    Mouse LD50 (oral) 521mg/kg
    Continued on Next Page
    3-Chlorophenol
    Chronic Toxic Effects        CARCINOGENIC EFFECTS : Not available.    
    MUTAGENIC EFFECTS : Not available.
    TERATOGENIC EFFECTS :Tumorigenic Effects:
    Mouse TDLo (dermal) 6000 mg/kg/15 weeks, intermittent.
    Toxic Effects:
    Tumorigenic - Equivocal tumorigenic agent by RTECS criteria.
    Skin and Appendages - Tumors.
    DEVELOPMENTAL TOXICITY: Not available.
    Repeated exposure of the eyes to a low level of dust can produce eye irritation. Repeated skin exposure can produce
    local skin destruction, or dermatitis. Repeated inhalation of dust can produce varying degree of respiratory irritation or
    lung damage.
    Acute Toxic Effects        Corrosive to skin, eyes, and respiratory system. Liquid or spray mist may produce tissue damage, particularly in mucous    
    membranes of the eyes, mouth and respiratory tract. Skin contact may produce burns. Eye contact can result in corneal
    damage or blindness. Inhalation of the spray mist may produce severe irritation of respiratory tract, characterized by
    coughing, choking, or shortness of breath. Corrosive materials may cause serious injury if ingested.
    Harmful if ingested or inhaled. Minimize exposure to this material. Severe overexposure can result in injury or death.
    Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.

Section XII.        Ecological Information    
    Ecotoxicity        Not available.    
    Environmental Fate        3-Chlorophenol's production and use as an intermediate in organic synthesis may result in its release to the environment    
    through various waste streams. Based on a vapor pressure of 0.125 mm Hg at 25 deg C, 3-chlorophenol is expected to
    exist solely as a vapor in the ambient atmosphere. Vapor-phase 3-chlorophenol is degraded in the atmosphere by reaction
    with photochemically-produced hydroxyl radicals with an atmospheric half-life of about 12 hours. 3-Chlorophenol absorbs
    light in the deep UV, but since there is some overlap between its absorption spectrum and the tropospheric solar
    spectrum, degradation by natural sunlight is possible. 3-Chlorophenol is expected to exhibit high mobility in soils based
    upon a Koc value of 350. Volatilization from dry soil surfaces is not expected based upon the vapor pressure of this
    compound. Volatilization from moist soil surfaces is expected to be slow based upon the estimated Henry's Law constant
    of 8.5X10-7 atm-cu m/mol. This compound is expected to biodegrade in soils under both aerobic and anaerobic conditions
    with observed half-lives in the range of several days to weeks. In water, 3-chlorophenol is not expected to adsorb to
    sediment or particulate matter given its Koc value. This compound is expected to volatilize slowly from water surfaces
    given its Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 49 and 361 days,
    respectively. 3-Chlorophenol is expected to biodegrade in aquatic environments with a half-life of about 36 days. A pKa
    value of 9.12 indicates that the dissociated form of 3-chlorophenol will only be significant under alkaline conditions. The
    potential for bioconcentration in aquatic organisms is considered low based on BCF values in the range 5-16 measured in
    carp. Occupational exposure may be through inhalation and dermal contact with this compound at workplaces where
    3-chlorophenol is produced or used. The general population may be exposed to 3-chlorophenol through the ingestion of
    contaminated water sources.

Section XIII. Disposal Considerations
    Waste Disposal        Recycle to process, if possible. Consult your local regional authorities. You may be able to dissove or mix material with a    
    combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all
    federal, state and locl regulations when disposing of the substance.

Section XIV. Transport Information
    DOT Classification        CLASS 6.1: Poisonous material.    
    PIN Number
    Proper Shipping Name        Chlorophenols, solid    
    Packing Group (PG)        III    
    DOT Pictograms

Section XV. Other Regulatory Information and Pictograms
    TSCA Chemical Inventory        This compound is ON the EPA Toxic Substances Control Act (TSCA) inventory list.    
    (EPA)
    WHMIS Classification        CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).    
    (Canada)        CLASS E: Corrosive solid.    
    EINECS Number (EEC) 203-582-6
    EEC Risk Statements        R20/21/22- Harmful by inhalation, in contact with skin and if swallowed.    
    R34- Causes burns.
    Japanese Regulatory Data
    Not available.
    Continued on Next Page


SECTION 16 - ADDITIONAL INFORMATION
N/A

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