Recommended Suppliersmore
Isopropyl acetate 108-21-4 MSDS
Name: Iso-Propyl Acetate Material Safety Data Sheet
Synonym: 2-Acetoxypropane; 2-Propyl Acetate
CAS: 108-21-4
Section 1 - Chemical Product   MSDS Name:Iso-Propyl Acetate Material Safety Data Sheet
Synonym:2-Acetoxypropane; 2-Propyl Acetate

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
108-21-4 Isopropyl acetate 100 203-561-1
Hazard Symbols: XI F
Risk Phrases: 11 36 66 67

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Highly flammable. Irritating to eyes. Repeated exposure may cause skin dryness or cracking. Vapours may cause drowsiness and dizziness.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Prolonged and/or repeated contact may cause defatting of the skin and dermatitis. May cause skin burns. Chronic exposure may cause liver damage.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. Inhalation of vapor may cause respiratory tract irritation.
May cause effects similar to those described for ingestion. May cause narcotic effects in high concentration. Causes irritation of mucous membrane.
Chronic:
Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion. Prolonged or repeated skin contact may cause defatting and dermatitis. Chronic exposure may cause liver damage.

Section 4 - FIRST AID MEASURES
  Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
  General Information:
Containers can build up pressure if exposed to heat and/or fire. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. Combustion generates toxic fumes. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Flammable liquid and vapor. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Water may be ineffective. Use water spray, dry chemical, carbon dioxide, or alcohol-resistant foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 108-21-4: United Kingdom, WEL - STEL: 200 ppm STEL; 849 mg/m3 STEL United States OSHA: 250 ppm TWA; 950 mg/m3 TWA Belgium - TWA: 250 ppm VLE; 1055 mg/m3 VLE Belgium - STEL: 310 ppm VLE; 1309 mg/m3 VLE France - VME: 250 ppm VME; 950 mg/m3 VME France - VLE: 300 ppm VLE; 1140 mg/m3 VLE Germany: 100 ppm TWA; 420 mg/m3 TWA Malaysia: 250 ppm TWA; 1040 mg/m3 TWA Spain: 250 ppm VLA-ED; 1060 mg/m3 VLA-ED Spain: 310 ppm VLA-EC; 1315 mg/m3 VLA-EC Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Liquid
Color: colorless
Odor: acetic odor
pH: Not available.
Vapor Pressure: 47.5 mm Hg @20C
Viscosity: 0.60mPa.s @20c
Boiling Point: 85 deg C
Freezing/Melting Point: -62 deg C
Autoignition Temperature: 479 deg C ( 894.20 deg F)
Flash Point: 2 deg C ( 35.60 deg F)
Explosion Limits, lower: 1.76
Explosion Limits, upper: 7.2
Decomposition Temperature:
Solubility in water: Slightly soluble in water
Specific Gravity/Density: 0.87
Molecular Formula: CH3COOCH(CH3)2
Molecular Weight: 102.0688

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Stable under normal temperatures and pressures..
Incompatibilities with Other Materials:
Oxidizing agents, bases, acids.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 108-21-4: AI4930000 LD50/LC50:
CAS# 108-21-4: Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = 50600 mg/m3/8H; Oral, rabbit: LD50 = 6946 mg/kg; Oral, rat: LD50 = 6750 mg/kg; Skin, rabbit: LD50 = >20 mL/kg.
Carcinogenicity:
Isopropyl acetate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
 

Section 13 - DISPOSAL CONSIDERATIONS
  Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.

Section 14 - TRANSPORT INFORMATION
 
IATA
Shipping Name: ISOPROPYL ACETATE
Hazard Class: 3
UN Number: 1220
Packing Group: II
IMO
Shipping Name: ISOPROPYL ACETATE
Hazard Class: 3
UN Number: 1220
Packing Group: II
RID/ADR
Shipping Name: ISOPROPYL ACETATE
Hazard Class: 3
UN Number: 1220
Packing group: II

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI F
Risk Phrases:
R 11 Highly flammable.
R 36 Irritating to eyes.
R 66 Repeated exposure may cause skin dryness or
cracking.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 23 Do not inhale gas/fumes/vapour/spray.
S 29 Do not empty into drains.
S 33 Take precautionary measures against static
discharges.
WGK (Water Danger/Protection)
CAS# 108-21-4: 1
Canada
CAS# 108-21-4 is listed on Canada's DSL List.
CAS# 108-21-4 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 108-21-4 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

Home   |   Announcement   |   Partners   |   Business Cooperation   |   Suppliers   |   Products    |   About Us   |   Contact Us   |   Privacy Policy   |   Terms & Conditions   |   Legal Statement

Copyright © 2013-2016 MOLBASE All Rights Reserved ICP Shanghai 14014220