propionitrile 107-12-0 MSDS
Name: Propionitrile 99% Material Safety Data Sheet
Synonym: Cyanoethane; Ethyl cyanide; Hydrocyanic ether; Propionic nitril
CAS: 107-12-0
Section 1 - Chemical Product   MSDS Name:Propionitrile 99% Material Safety Data Sheet
Synonym:Cyanoethane; Ethyl cyanide; Hydrocyanic ether; Propionic nitril

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
107-12-0 Propionitrile 99 203-464-4
Hazard Symbols: T F
Risk Phrases: 11 23/24/25

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Highly flammable. Toxic by inhalation, in contact with skin and if swallowed.Possible risks of irreversible effects.
Potential Health Effects
Eye:
Vapors cause eye irritation.
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
Ingestion:
May be fatal if swallowed. Contains cyanide.
Inhalation:
Vapors may cause dizziness or suffocation. Vapor or mist is irritating to the mucous membranes and upper respiratory tract.
Chronic:
May cause cyanosis - a blue-gray coloring of the skin and lips caused by a lack of oxygen. Massive doses may produce, without warning, sudden loss of consciousness and prompt death from respiratory arrest.

Section 4 - FIRST AID MEASURES
  Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. Do NOT use mouth-to-mouth resuscitation. Administer oxygen. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Treat symptomatically and supportively.
Antidote: Always have a cyanide antidote kit on hand when working with cyanide compounds. Get medical advice to use. The combination of sodium thiosulfate and hydroxycobalamin has been used as an effective antidote.

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Containers may explode in the heat of a fire.
Flammable liquid and vapor. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Do NOT use water directly on fire. Use water spray to cool fire-exposed containers. Use foam, dry chemical, or carbon dioxide. Water may be ineffective. Do NOT use straight streams of water. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Do not get on skin or in eyes. Do not ingest or inhale.
Use with adequate ventilation. Wash clothing before reuse. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 107-12-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Clear liquid
Color: Clear, Colorless Liquid
Odor: Pleasant, ethereal-sweetish odor
pH: Not available.
Vapor Pressure: 40 mmHg @ 23 C
Viscosity: 0.44 mPas 20 deg C
Boiling Point: 97 deg C @ 760.00mm Hg
Freezing/Melting Point: -93 deg C
Autoignition Temperature: 510 deg C ( 950.00 deg F)
Flash Point: 6 deg C ( 42.80 deg F)
Explosion Limits, lower: 3.10 vol %
Explosion Limits, upper: .00 vol %
Decomposition Temperature:
Solubility in water: Soluble.
Specific Gravity/Density: .7720g/cm3
Molecular Formula: C3H5N
Molecular Weight: 55.08

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong reducing agents, strong acids, strong bases.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 107-12-0: UF9625000 LD50/LC50:
CAS# 107-12-0: Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, mouse: LC50 = 163 ppm/1H; Oral, mouse: LD50 = 35797 ug/kg; Oral, rat: LD50 = 39 mg/kg; Skin, rabbit: LD50 = 210 uL/kg.
Carcinogenicity:
Propionitrile - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
  Ecotoxicity:
Estimated BCF Value = 0.78. This value suggests that propionitrile is not expected to bioconcentrate in aquatic organisms. Estimated Koc Value = 1.2. This suggests that it will not be expected to adsorb significantly to soil.

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Shipping Name: PROPIONITRILE
Hazard Class: 3 (6.1)
UN Number: 2404
Packing Group: II
IMO
Shipping Name: PROPIONITRILE
Hazard Class: 3.2 (6.1)
UN Number: 2404
Packing Group: II
RID/ADR
Shipping Name: PROPIONITRILE
Hazard Class: 3
UN Number: 2404
Packing group: II
USA RQ: CAS# 107-12-0: 10 lb final RQ; 4.54 kg final RQ

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T F
Risk Phrases:
R 11 Highly flammable.
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
Safety Phrases:
S 9 Keep container in a well-ventilated place.
S 16 Keep away from sources of ignition - No
smoking.
S 27 Take off immediately all contaminated clothing.
S 33 Take precautionary measures against static
discharges.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 107-12-0: 1
Canada
CAS# 107-12-0 is listed on Canada's DSL List.
CAS# 107-12-0 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 107-12-0 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

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