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Description Feedback
4-Hydroxybenzoic acid, also known as p-hydroxybenzoic acid (PHBA), is a monohydroxybenzoic acid, a phenolic derivative of benzoic acid. It is a white crystalline solid that is slightly soluble in water and chloroform but more soluble in polar organic solvents such as alcohols and acetone. 4-Hydroxybenzoic acid is primarily known as the basis for the preparation of its esters, known as parabens, which are used as preservatives in cosmetics and some ophthalmic solutions. It is isomeric with 2-hydroxybenzoic acid, known as salicylic acid, a precursor to aspirin.

Properties Feedback
Appearance & Physical State:White to beige crystalline powder
Density:1.46 g/cm3
Melting Point:214-217ºC
Boiling Point:336.2ºC at 760 mmHg
Flash Point:199ºC
Refractive Index:1.53
Water Solubility:5 g/L (20 ºC)
Stability:Stable under normal temperatures and pressures.
Storage Condition:Store in a cool, dry place. Keep container closed when not in use.

Safety Info Feedback
Safety Statements:S26-S37/39
HS Code:2916399090
WGK Germany:1
Risk Statements:R36/37/38
Hazard Codes:Xi

GC Analytical Method Total: 5 GC Analytical Method
Van Den Dool and Kratz RI, non-polar column, custom temperature program [Detail]
Column type Active phase Temperature (C) Retention Index (I) Reference
Capillary VF-5MS 1537.7 Tret'yakov, 2008
Normal alkane RI, non-polar column, temperature ramp [Detail]
Column type Active phase Temperature (C) Retention Index (I) Reference
Capillary HP-5 MS 1558. Jerkovic, Hegic, et al., 2010


Synthesis Route Total: 319 Synthesis Route
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Precursor and Product