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Description Feedback
Triethyl phosphonoacetate is a reagent for organic synthesis used in the Horner-Wadsworth-Emmons reaction (HWE) or the Horner-Emmons modification.
Triethyl phosphonoacetate can be added dropwise to sodium methoxide solution to prepare a phosphonate ylide. It has an acidic proton that can easily be abstracted by a weak base. When used in an HWE reaction with a carbonyl the resulting alkene formed is usually the E alkene, and is generated with excellent regioselectivity.

Properties Feedback
Appearance & Physical State:colorless and light yellow transparent liquid
Density:1.13
Melting Point:-24ºC
Boiling Point:260-262ºC
Flash Point:141.6ºC
Refractive Index:1.43-1.432
Stability:Stable under normal temperatures and pressures.
Storage Condition:Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Safety Info Feedback
RTECS:AG9800000
Safety Statements:S26-S37/39-S61
HS Code:2931901990
WGK Germany:3
RIDADR:UN 3082
Risk Statements:R36/37/38; R51/53
Hazard Codes:Xi

MSDS


Synthesis Route Total: 27 Synthesis Route
 
105-36-2
122-52-1
~99%
867-13-0
View Detail
 
105-39-5
122-52-1
~94%
867-13-0
View Detail

Precursor and Product