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5-Chloro-2-nitroanisole

CAS No.: 6627-53-8
Synonyms:
Formula: C7H6ClNO3
Exact Mass: 187.00400
Molecular Weight: 187.58000
PSA: 55.05000
LogP: 2.78000
Reference Price: $2,664/kg Post Buying Request
Description Feedback
5-Chloro-2-nitroanisole is involved in the synthesis of orally bioavailable anaplastic lymphoma kinases (ALK) inhibitors as anticancer drugs. In addition it is used in the synthesis of kinesin spindle protein (KSP) inhibitors which are responsible for the spindle pole separation which occurs during mitosis in cancer cells.

Properties Feedback
Appearance & Physical State:slightly yellow to green crystalline powder
Density:1.366g/cm3
Melting Point:70-72ºC
Boiling Point:289.1ºC at 760mmHg
Flash Point:128.7ºC
Refractive Index:1.559

Safety Info Feedback
Safety Statements:S26-S37/39
HS Code:2909309090
WGK Germany:3
Risk Statements:R36/37/38
Hazard Codes:Xi

MSDS


Synthesis Route Total: 12 Synthesis Route
 
124-41-4
610-40-2
~53%
89-21-4
6627-53-8
View Detail
123-91-1
67-56-1
672295-04-4
124-41-4
6627-53-8
View Detail

Precursor and Product