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Bilirubin

CAS No.: 635-65-4
Synonyms:
Formula: C33H36N4O6
Exact Mass: 584.26300
Molecular Weight: 584.66200
PSA: 164.38000
LogP: 5.18880
Reference Price: $4,160/kg Post Buying Request
Description Feedback
Bilirubin (formerly referred to as haematoidin) is a yellow compound that occurs in the normal catabolic pathway that breaks down heme in vertebrates. This catabolism is a necessary process in the body's clearance of waste products that arise from the destruction of aged red blood cells. First the hemoglobin gets stripped of the heme molecule which thereafter passes through various processes of porphyrin catabolism, depending on the part of the body in which the breakdown occurs. For example, the molecules excreted in the urine differ from those in the feces. The production of biliverdin from heme is the first major step in the catabolic pathway, after which the enzyme biliverdin reductase performs the second step, producing bilirubin from biliverdin.
Bilirubin is excreted in bile and urine, and elevated levels may indicate certain diseases. It is responsible for the yellow color of bruises and the yellow discoloration in jaundice. Its subsequent breakdown products, such as stercobilin, cause the brown color of feces. A different breakdown product, urobilin, is the main component of the straw-yellow color in urine.
It has also been found in plants.

Properties Feedback
Appearance & Physical State:light orange to brown crystalline powder
Density:1.374 g/cm3
Melting Point:192ºC
Boiling Point:925.2ºC at 760 mmHg
Flash Point:513.3ºC
Stability:Stable. Refrigerate.
Storage Condition:-20ºC

Safety Info Feedback
RTECS:DU3038000
Safety Statements:S22; S24/25; S36; S26
HS Code:29339990
WGK Germany:2
Risk Statements:R62
Hazard Codes:Xn

MSDS


Synthesis Route Total: 8 Synthesis Route
 
35677-91-9
~82%
635-65-4
View Detail
 
80575-27-5
35991-50-5
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Precursor and Product