Ethyl diazoacetate

CAS No.: 623-73-4
Synonyms:
Formula: C4H6N2O2
Exact Mass: 114.04300
Molecular Weight: 114.10300
PSA: 63.69000
LogP: -0.06884
Description Feedback
Ethyl diazoacetate (N=N=CHC(O)OC2H5) is a diazo compound and a reagent in organic chemistry. It was discovered by Theodor Curtius in 1883. The compound can be prepared by reaction of the ethyl ester of glycine with sodium nitrite and sodium acetate in water.
It is used in the cyclopropanation of alkenes.
Although the compound is hazardous it is used in chemical industry. Procedures for safe industrial handling have been published

Properties Feedback
Appearance & Physical State:colourless liquid
Density:1.085
Melting Point:-22ºC
Boiling Point:140-141ºC (720 mmHg)
Flash Point:46ºC
Refractive Index:1.46
Storage Condition:2-8ºC

Safety Info Feedback
Symbol:
GHS02

GHS07

GHS08
Sign:Warning
hazard declaration:H226; H242; H302; H351
hazard declaration add:
waring notice:P281
Hazard Class:3.2
Safety Statements:S36/37
HS Code:2927000090
Packing Group:III
WGK Germany:3
RIDADR:UN 1993
Risk Statements:R5; R10; R22; R40
Hazard Codes:Xn

GC Analytical Method Total: 3 GC Analytical Method
Normal alkane RI, non-polar column, temperature ramp [Detail]
Column type Active phase Temperature (C) Retention Index (I) Reference
Capillary HP-5 MS 840. Kornilova, Ukolov, et al., 2012
Normal alkane RI, non-polar column, temperature ramp [Detail]
Column type Active phase Temperature (C) Retention Index (I) Reference
Capillary HP-5 MS 867. Kornilova, Ukolov, et al., 2012
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MSDS


Synthesis Route Total: 22 Synthesis Route
 
623-33-6
~82%
623-73-4
View Detail
 
10271-27-9
~65%
623-73-4
View Detail

Precursor and Product