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N'-hydroxy-N-pyridin-3-yloctanediamide

CAS No.: 382180-17-8
Synonyms:
Formula: C13H19N3O3
Exact Mass: 265.14300
Molecular Weight: 265.30800
PSA: 91.32000
LogP: 2.33000
Reference Price: $3,696/g Post Buying Request
Description Feedback
Pyroamide is a histone decetylase inhibitor (HDCi), a novel class of anti-neoplastic agent that acts by enhancing acetylation of histones, promoting uncoiling of chromatin and activation of genes implicated in the regulation of cell survival such as poliferation, differentiation and apoptosis. Pyroamide is known to potently inhibits affinity purified HDAC1. Also inhibits the growth of tumor cells in vitro and in vivo. Induces p21/WAF1 expression in tumor cells.

Properties Feedback
Density:1.215 g/cm3
Refractive Index:1.569

Safety Info Feedback
Symbol:
GHS07
Sign:Warning
hazard declaration:H302
hazard declaration add:
waring notice:
HS Code:2933399090


Synthesis Route Total: 2 Synthesis Route
 
405096-07-3
~46%
382180-17-8
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3946-32-5
382180-17-8
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Precursor and Product
Precursor:
405096-07-3
3946-32-5
Total: 2
Product:
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