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Description Feedback
2,3-Dihydroxybenzoic acid is a natural phenol found in Phyllanthus acidus and in the aquatic fern Salvinia molesta. It is also abundant in the fruits of Flacourtia inermis. It is a dihydroxybenzoic acid, a type of organic compound. The colorless solid occurs naturally, being formed via the shikimate pathway. It is incorporated into various siderophores, which are molecules that strongly complex iron ions for absorption into bacteria. 2,3-DHB consists of a catechol group, which upon deprotonation binds iron centers very strongly, and the carboxylic acid group by which the ring attaches to various scaffolds via amide linkages. A famous high affinity siderophore is enterochelin, which contains three dihydroxybenzoyl substituents linked to the depsipeptide of serine.
It is a potentially useful iron-chelating drug and has antimicrobial properties
2,3-Dihydroxybenzoic acid is also a product of human aspirin metabolism.

Properties Feedback
Appearance & Physical State:white crystalline powder
Density:1.559 g/cm3
Melting Point:204-208ºC
Boiling Point:208ºC
Flash Point:187.2ºC
Storage Condition:2-8°C

Safety Info Feedback
RTECS:DG8576490
Safety Statements:S26-S37/39
HS Code:2918290000
WGK Germany:2
Risk Statements:R36/37/38
Hazard Codes:Xi

GC Analytical Method Total: 1 GC Analytical Method
Normal alkane RI, non-polar column, isothermal [Detail]
Column type Active phase Temperature (C) Retention Index (I) Reference
Packed Apieson L 140. 1372. Hedin, Minyard, et al., 1967
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MSDS


Synthesis Route Total: 44 Synthesis Route
 
24677-78-9
~83%
303-38-8
View Detail
 
3943-73-5
~72%
303-38-8
View Detail

Precursor and Product