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pioglitazone

CAS No.: 111025-46-8
Synonyms:
Formula: C19H21ClN2O3S
Exact Mass: 392.09600
Molecular Weight: 392.90000
PSA: 93.59000
LogP: 4.29040
Reference Price: $819/kg Post Buying Request
Description Feedback
Pioglitazone (brand name Actos) is a prescription drug of the thiazolidinedione (TZD) class with hypoglycemic (antihyperglycemic, antidiabetic) action to treat diabetes. While pioglitazone does decrease blood sugar levels, studies on the main cardiovascular outcomes have not yielded statistically significant results.
Its cardiovascular safety profile compares favorably with that of rosiglitazone, which was withdrawn from some markets after concerns about an increased risk of cardiac events. Pioglitazone has been found to be associated with bladder tumors and has been withdrawn in some countries.
Actos was the tenth-best selling drug in the U.S. in 2008, with sales exceeding $2.4 billion.

Properties Feedback
Appearance & Physical State:White powder
Density:1.26 g/cm3
Melting Point:183-184ºC
Boiling Point:575.4ºC at 760 mmHg
Flash Point:301.8ºC
Storage Condition:Store in original container in a cool dark place.
Vapor Pressure:3.03E-13mmHg at 25°C

Safety Info Feedback
Safety Statements:S36/37
Risk Statements:R20/21/22
Hazard Codes:F; C

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