C 2H 5O+ + CH 3OH → C 3H 8O 2 + H+
2-Methoxyethanol is used as a solvent for many different purposes such as varnishes, dyes, and resins. It is also used as an additive in airplane deicing solutions. In organometallic chemistry it is commonly used for the synthesis of Vaska's complex and related compounds such as carbonylchlorohydridotris(triphenylphosphine)ruthenium (II). During these reactions the alcohol acts as a source of hydride and carbon monoxide.
2-Methoxyethanol is toxic to the bone marrow and testicles. Workers exposed to high levels are at risk for granulocytopenia, macrocytic anemia, oligospermia, and azoospermia.
The methoxyethanol is converted by alcohol dehydrogenase into methoxyacetic acid which is the substance which causes the harmful effects. Both ethanol and acetate have a protecting effect. The methoxyacetate can enter the Krebs cycle where it forms methoxycitrate.
|Appearance & Physical State:||colorless clear liquid|
|Stability:||Stable, but contact with air may lead to the formation of explosive peroxides. A peroxide test should be carried out before this material is used if it has been exposed to air for some time, especially if it is to be purified by distillation. Contact with|
|Vapor Pressure:||6.17 mm Hg ( 20 °C)|
|Vapor Density:||2.62 (vs air)|
Safety Info Feedback
|hazard declaration:||H226; H302 + H312 + H332; H360FD; H370; H373|
|hazard declaration add:|
|waring notice:||P201; P210; P260; P302 + P352 + P312; P304 + P340 + P312; P308 + P311|
|Risk Statements:||R10; R20/21/22; R60; R61|
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